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Publications

Challenging Roadblocks to Cancer Cure.

Loda M. Challenging Roadblocks to Cancer Cure. Cancer Res. 2016;76(17):4924-30. doi:10.1158/0008-5472.CAN-16-1443

Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta.

Kanost MR, Arrese EL, Cao X, et al. Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta. Insect Biochem Mol Biol. 2016;76:118-47. doi:10.1016/j.ibmb.2016.07.005

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum.

Miles A, Iqbal Z, Vauterin P, et al. Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum. Genome Res. 2016;26(9):1288-99. doi:10.1101/gr.203711.115

Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis.

Terao C, Raychaudhuri S, Gregersen PK. Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis. Annu Rev Genomics Hum Genet. 2016;17:273-301. doi:10.1146/annurev-genom-090314-045919

Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD.

Wagner EK, Raychaudhuri S, Villalonga MB, et al. Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD. Sci Rep. 2016;6:31531. doi:10.1038/srep31531

A substrate-driven allosteric switch that enhances PDI catalytic activity.

Bekendam RH, Bendapudi PK, Lin L, et al. A substrate-driven allosteric switch that enhances PDI catalytic activity. Nat Commun. 2016;7:12579. doi:10.1038/ncomms12579

A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking.

Huan T, Joehanes R, Schurmann C, et al. A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking. Hum Mol Genet. 2016. doi:10.1093/hmg/ddw288

Seipin is required for converting nascent to mature lipid droplets.

Wang H, Becuwe M, Housden BE, et al. Seipin is required for converting nascent to mature lipid droplets. Elife. 2016;5. doi:10.7554/eLife.16582

Leveraging human genetics to guide drug target discovery.

Stitziel NO, Kathiresan S. Leveraging human genetics to guide drug target discovery. Trends Cardiovasc Med. 2016. doi:10.1016/j.tcm.2016.08.008

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons.

Habib N, Li Y, Heidenreich M, et al. Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons. Science. 2016;353(6302):925-8. doi:10.1126/science.aad7038