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Publications

Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.

Wagner FF, Bishop JA, Gale JP, et al. Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. ACS Chem Biol. 2016;11(7):1952-63. doi:10.1021/acschembio.6b00306

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.

Scocchera E, Reeve SM, Keshipeddy S, et al. Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens. ACS Med Chem Lett. 2016;7(7):692-6. doi:10.1021/acsmedchemlett.6b00120

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma.

Powers JT, Tsanov KM, Pearson DS, et al. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature. 2016;535(7611):246-51. doi:10.1038/nature18632

Ipilimumab for Patients with Relapse after Allogeneic Transplantation.

Davids MS, Kim HT, Bachireddy P, et al. Ipilimumab for Patients with Relapse after Allogeneic Transplantation. N Engl J Med. 2016;375(2):143-53. doi:10.1056/NEJMoa1601202

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease.

Burberry A, Suzuki N, Wang JY, et al. Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Sci Transl Med. 2016;8(347):347ra93. doi:10.1126/scitranslmed.aaf6038

Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases.

Li Y, Kellis M. Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases. Nucleic Acids Res. 2016. doi:10.1093/nar/gkw627

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

Legge SE, Hamshere ML, Ripke S, et al. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. Mol Psychiatry. 2016. doi:10.1038/mp.2016.97

An Outbreak of Ebola Virus Disease in the Lassa Fever Zone.

Goba A, Khan H, Fonnie M, et al. An Outbreak of Ebola Virus Disease in the Lassa Fever Zone. J Infect Dis. 2016. doi:10.1093/infdis/jiw239

Comparative transcriptomics across the prokaryotic tree of life.

Cohen O, Doron S, Wurtzel O, et al. Comparative transcriptomics across the prokaryotic tree of life. Nucleic Acids Res. 2016;44(W1):W46-53. doi:10.1093/nar/gkw394

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein.

Pak CW, Kosno M, Holehouse AS, et al. Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein. Mol Cell. 2016;63(1):72-85. doi:10.1016/j.molcel.2016.05.042