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Publications

Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders.

Yang J, Xu Y, Ziehr DR, et al. Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders. Science (New York, N.Y.). 2025;389(6757):eado2403. doi:10.1126/science.ado2403

Brain endothelial gap junction coupling enables rapid vasodilation propagation during neurovascular coupling.

Krolak T, Kaplan L, Navas K, et al. Brain endothelial gap junction coupling enables rapid vasodilation propagation during neurovascular coupling. Cell. 2025;188(18):5003-5019.e22. doi:10.1016/j.cell.2025.06.030

The diabetes gene Tcf7l2 organizes gene expression in the liver and regulates amino acid metabolism.

Krawczyk J, O’Connor W, Vendramini P, et al. The diabetes gene Tcf7l2 organizes gene expression in the liver and regulates amino acid metabolism. Molecular metabolism. 2025;99:102208. doi:10.1016/j.molmet.2025.102208

Absolute and relative risks of mental disorders in families: a Danish register-based study.

Pedersen CB, Pedersen MG, Antonsen S, et al. Absolute and relative risks of mental disorders in families: a Danish register-based study. The lancet. Psychiatry. 2025;12(8):590-599. doi:10.1016/S2215-0366(25)00196-8

Publisher Correction: Comprehensive evaluation of phosphoproteomic-based kinase activity inference.

Müller-Dott S, Jaehnig EJ, Munchic KP, et al. Publisher Correction: Comprehensive evaluation of phosphoproteomic-based kinase activity inference. Nature communications. 2025;16(1):6591. doi:10.1038/s41467-025-62094-1

Direct genetic transformation bypasses tumor-associated DNA methylation alterations.

Hetzel S, Hodis E, Triglia ET, et al. Direct genetic transformation bypasses tumor-associated DNA methylation alterations. Genome biology. 2025;26(1):212. doi:10.1186/s13059-025-03650-2

Pancreatic injury induces β-cell regeneration in axolotl.

Powell CJ, Singer HD, Juarez AR, et al. Pancreatic injury induces β-cell regeneration in axolotl. Developmental dynamics : an official publication of the American Association of Anatomists. 2025. doi:10.1002/dvdy.70060

OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation.

Li B, Sakaguchi T, Tani H, et al. OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation. Science immunology. 2025;10(109):eadm6843. doi:10.1126/sciimmunol.adm6843

Preparation and analysis of monotypic and organotypic tumor spheroids.

Domingues ACM, Palin C, Sun Y, et al. Preparation and analysis of monotypic and organotypic tumor spheroids. Methods in cell biology. 2025;196:139-159. doi:10.1016/bs.mcb.2024.11.003

Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation.

Wang JS, Strauss K, Houghton C, et al. Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation. Bone research. 2025;13(1):70. doi:10.1038/s41413-025-00440-1