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Publications

Tissue and cellular spatiotemporal dynamics in colon aging.

Daly AC, Cambuli F, Äijö T, et al. Tissue and cellular spatiotemporal dynamics in colon aging. Nature biotechnology. 2025. doi:10.1038/s41587-025-02830-6

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function.

Asadollahi R, Ahmad A, Boonsawat P, et al. Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function. Nature genetics. 2025. doi:10.1038/s41588-025-02361-5

Mapping Plasmodium transitions and interactions in the Anopheles female.

Yan Y, Verzier LH, Cheung E, et al. Mapping Plasmodium transitions and interactions in the Anopheles female. Nature. 2025. doi:10.1038/s41586-025-09653-0

Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma.

Nopsopon T, Cabrera-Perez J, Lee PY, et al. Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma. Respiratory research. 2025;26(1):291. doi:10.1186/s12931-025-03373-9

An ingestible capsule for luminance-based diagnosis of mesenteric ischemia.

Chen J, Alexiev A, Sergnese A, et al. An ingestible capsule for luminance-based diagnosis of mesenteric ischemia. Science robotics. 2025;10(107):eadx1367. doi:10.1126/scirobotics.adx1367

Kcnn4/KCa3.1 inhibition blunts polycystic kidney disease progression in mouse models.

Yao G, Kurbegovic A, Parrot C, et al. Kcnn4/KCa3.1 inhibition blunts polycystic kidney disease progression in mouse models. JCI insight. 2025;10(20). doi:10.1172/jci.insight.191311

Combining Polygenic Risk With LDL, CRP, and Lp(a) to Predict Coronary Artery Disease: UK Biobank Study.

Khetarpal SA, Shi Z, Goyal A, et al. Combining Polygenic Risk With LDL, CRP, and Lp(a) to Predict Coronary Artery Disease: UK Biobank Study. Journal of the American College of Cardiology. 2025. doi:10.1016/j.jacc.2025.08.069

Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial.

Shimano KA, Grimes AB, Kaicker S, et al. Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial. JAMA. 2025. doi:10.1001/jama.2025.18168

Virologic characteristics of SARS-CoV-2 infection across evolving omicron subvariants.

Boucau J, Glover OT, Marino C, et al. Virologic characteristics of SARS-CoV-2 infection across evolving omicron subvariants. JCI insight. 2025. doi:10.1172/jci.insight.192228

Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard.

Lin YY, Breuer K, Weichenhan D, et al. Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard. Nucleic acids research. 2025;53(19). doi:10.1093/nar/gkaf970