Ether lipids influence cancer cell fate by modulating iron uptake. Mansell RP, Müller S, Yang JS, et al. Ether lipids influence cancer cell fate by modulating iron uptake. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2024.03.20.585922 PMCID PMC10983928 Read more
Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state. Chiasson-MacKenzie C, Zhang Y, O’Loughlin E, et al. Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2024.08.30.610360 PMCID PMC11398422 Read more
Transfer learning enables discovery of sub-micromolar antibacterials for ESKAPE pathogens from ultra-large chemical spaces. GarcÃa-Ortegón M, Seal S, Geddes E, et al. Transfer learning enables discovery of sub-micromolar antibacterials for ESKAPE pathogens from ultra-large chemical spaces. Chemical science. 2025. doi:10.1039/d5sc03055b PMCID PMC12523573 Read more
The regulatory landscape of nascent transcription in human health and disease. Shah SR, Chen Y, Leung AK, et al. The regulatory landscape of nascent transcription in human health and disease. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.24.676871 Read more
Differentiation stage-specific use of cap-independent and cap-dependent translation initiation in hematopoiesis. Mazzola MC, Zhao T, Kiem A, et al. Differentiation stage-specific use of cap-independent and cap-dependent translation initiation in hematopoiesis. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.24.678136 Read more
Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases. Koh B, Oz STG, Sato R, et al. Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.23.677874 Read more
Defining the vascular niche of human adipose tissue across metabolic states. AlZaim I, Hassan MN, Schröter M, et al. Defining the vascular niche of human adipose tissue across metabolic states. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2024.09.22.610444 Read more
Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons. Uyan Ö, Sambare S, Oomen ME, et al. Dynamic changes in chromosome and nuclear architecture during maturation of normal and ALS C9orf72 motor neurons. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.22.677835 Read more
Dual Modes of Gene Regulation by CDK12. Wang Y, Baluapuri A, Manokaran C, et al. Dual Modes of Gene Regulation by CDK12. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.22.677923 Read more
Mapping disease critical spatially variable gene programs by integrating spatial transcriptomics with human genetics. Lee H, Sun H, Cao X, et al. Mapping disease critical spatially variable gene programs by integrating spatial transcriptomics with human genetics. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.24.678397 Read more