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Publications

Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts.

Konigsberg IR, Vargas LB, Pratte KA, et al. Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.01.25328699

A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.

Atabaki NN, Coral DE, Pomares-Millan H, et al. A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.02.25328773

Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk.

Cudic M, Tubbs JD, Ge T, Smoller JW. Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.06.04.25328987

Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior.

Gunter-Rahman F, Mallett S, White F, et al. Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior. iScience. 2025;28(6):112636. doi:10.1016/j.isci.2025.112636

Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation.

Kaas M, Chofflet N, Bicer D, et al. Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation. Research square. 2025. doi:10.21203/rs.3.rs-5928514/v1

Rapid emergence of resistance to broad-spectrum direct antimicrobial activity of avibactam.

Nägeli M, Rodriguez S, Iradukunda A, Manson AL, Earl AM, Brennan-Krohn T. Rapid emergence of resistance to broad-spectrum direct antimicrobial activity of avibactam. Microbiology spectrum. 2025;13(8):e0324124. doi:10.1128/spectrum.03241-24

Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape.

Muir DF, Asper GPR, Notin P, et al. Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape. Science (New York, N.Y.). 2025;388(6752):eadu1058. doi:10.1126/science.adu1058

Pan-viral ORFs discovery using massively parallel ribosome profiling.

Weingarten-Gabbay S, Bauer MR, Stanton AC, et al. Pan-viral ORFs discovery using massively parallel ribosome profiling. Science (New York, N.Y.). 2025;388(6752):1218-1224. doi:10.1126/science.ado6670

A single dose of a CD137 antibody-drug conjugate protects rhesus macaque allogeneic HCT recipients against acute GVHD.

Gerdemann U, Kimler K, Warren MR, et al. A single dose of a CD137 antibody-drug conjugate protects rhesus macaque allogeneic HCT recipients against acute GVHD. Blood. 2025;146(9):1127-1141. doi:10.1182/blood.2024027239

Long-acting oral weekly risperidone (LYN-005) for schizophrenia in the USA (STARLYNG-1): a multicentre, open-label, non-randomised phase 3 trial.

Citrome L, Nagaraj N, Traverso G, Dumas T, Scranton R. Long-acting oral weekly risperidone (LYN-005) for schizophrenia in the USA (STARLYNG-1): a multicentre, open-label, non-randomised phase 3 trial. The lancet. Psychiatry. 2025;12(7):504-512. doi:10.1016/S2215-0366(25)00135-X