Publications

A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease.

Oh HSH, Urey DY, Karlsson L, et al. A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease. Nature medicine. 2025. doi:10.1038/s41591-025-03565-2

Targeted degradation of CDK9 potently disrupts the MYC-regulated network.

Toure MA, Motoyama K, Xiang Y, et al. Targeted degradation of CDK9 potently disrupts the MYC-regulated network. Cell chemical biology. 2025. doi:10.1016/j.chembiol.2025.03.001

Response Quantitative Trait Loci Unveiling Gene-Environment Interactions in Diseases.

Chen Y, Wang X, Chen C. Response Quantitative Trait Loci Unveiling Gene-Environment Interactions in Diseases. Biological psychiatry. 2025;97(8):756-757. doi:10.1016/j.biopsych.2025.02.003

Assessing the potential causal effects of 1099 plasma metabolites on 2099 binary disease endpoints.

Yin X, Li J, Bose D, et al. Assessing the potential causal effects of 1099 plasma metabolites on 2099 binary disease endpoints. Nature communications. 2025;16(1):3039. doi:10.1038/s41467-025-58129-2

Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features.

Klughammer J, Abravanel DL, Segerstolpe Åsa, et al. Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features. Nature medicine. 2025. doi:10.1038/s41591-025-03665-z

Tutorial: guidelines for quality filtering of whole-exome and whole-genome sequencing data for population-scale association analyses.

Sealock JM, Ivankovic F, Liao C, et al. Tutorial: guidelines for quality filtering of whole-exome and whole-genome sequencing data for population-scale association analyses. Nature protocols. 2025. doi:10.1038/s41596-025-01169-1

Enabling global image data sharing in the life sciences.

Bajcsy P, Bhattiprolu S, Börner K, et al. Enabling global image data sharing in the life sciences. Nature methods. 2025. doi:10.1038/s41592-024-02585-z

Correction: Respiratory infection‑ and asthma‑prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways.

Martino D, Schultz N, Kaur R, et al. Correction: Respiratory infection‑ and asthma‑prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways. Clinical epigenetics. 2025;17(1):53. doi:10.1186/s13148-025-01848-6

Tutorial: guidelines for quality filtering of whole-exome and whole-genome sequencing data for population-scale association analyses.

Sealock JM, Ivankovic F, Liao C, et al. Tutorial: guidelines for quality filtering of whole-exome and whole-genome sequencing data for population-scale association analyses. Nature protocols. 2025. doi:10.1038/s41596-025-01169-1

Semaglutide and bariatric surgery induce distinct changes in the composition of mouse white adipose tissue.

Emont MP, Essene AL, Gulko A, et al. Semaglutide and bariatric surgery induce distinct changes in the composition of mouse white adipose tissue. Molecular metabolism. 2025:102126. doi:10.1016/j.molmet.2025.102126