Publications

Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes.

Murthy VL, Piaggi P, Lin P, et al. Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes. Diabetes care. 2025;48(7):1260-1272. doi:10.2337/dc25-0151

Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage.

Braun F, Mandel AM, Blomberg L, et al. Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage. JCI insight. 2025;10(12). doi:10.1172/jci.insight.172370

Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin.

Beccari MS, Arnold-Garcia O, Baughn MW, et al. Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(21):e2502294122. doi:10.1073/pnas.2502294122

Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care.

Kreienkamp RJ, Deutsch AJ, Huerta-Chagoya A, et al. Type 1 Diabetes Polygenic Scores Improve Diagnostic Accuracy in Pediatric Diabetes Care. Hormone research in paediatrics. 2025:1-9. doi:10.1159/000546445

Prospects for understanding and exploiting the consequences of hyperactivation lethality.

Shaw K, Bernards R, Stegmaier K, Varmus H, Sellers WR. Prospects for understanding and exploiting the consequences of hyperactivation lethality. Trends in cancer. 2025;11(7):619-628. doi:10.1016/j.trecan.2025.04.009

Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation.

Kirmani S, Huan T, Van Amburg JC, et al. Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nature communications. 2025;16(1):4678. doi:10.1038/s41467-025-59333-w

An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration.

Leventhal MJ, Zanella CA, Kang B, et al. An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration. Nature communications. 2025;16(1):4441. doi:10.1038/s41467-025-59654-w

High-throughput single-cell density measurements enable dynamic profiling of immune cell and drug response from patient samples.

Wu W, Ishamuddin SH, Quinn TW, et al. High-throughput single-cell density measurements enable dynamic profiling of immune cell and drug response from patient samples. Nature biomedical engineering. 2025. doi:10.1038/s41551-025-01408-6

Genetic Risk Scores in Stroke Research and Care.

Bragazzi NL, Zhang L, Omarov M, Georgakis MK. Genetic Risk Scores in Stroke Research and Care. Stroke. 2025;56(8):2327-2336. doi:10.1161/STROKEAHA.125.050961

Body fluid biomarkers and psychosis risk in The Accelerating Medicines Partnership® Schizophrenia Program: design considerations.

Perkins DO, Jeffries CD, Clark SR, et al. Body fluid biomarkers and psychosis risk in The Accelerating Medicines Partnership® Schizophrenia Program: design considerations. Schizophrenia (Heidelberg, Germany). 2025;11(1):78. doi:10.1038/s41537-025-00610-4

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Publications

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