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Publications

Bench to all Bedsides in Genomics and Precision Medicine.

Tcheandjieu C, Robinson C, Natarajan P. Bench to all Bedsides in Genomics and Precision Medicine. Journal of the American Heart Association. 2025;14(11):e039202. doi:10.1161/JAHA.124.039202

Determinants and clinical impact of time to plasma exchange in patients with immune thrombotic thrombocytopenic purpura.

Tatake IJ, Wilkinson SC, Ruby KN, et al. Determinants and clinical impact of time to plasma exchange in patients with immune thrombotic thrombocytopenic purpura. Transfusion. 2025;65(7):1242-1250. doi:10.1111/trf.18291

Spatial multiomics decipher fibroblast-macrophage dynamics in systemic sclerosis.

Li Z, Rigau AR, Xie W, et al. Spatial multiomics decipher fibroblast-macrophage dynamics in systemic sclerosis. Annals of the rheumatic diseases. 2025;84(7):1231-1245. doi:10.1016/j.ard.2025.04.025

HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity.

Dobersch S, Yamamoto N, Schutter A, et al. HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity. Nature communications. 2025;16(1):4866. doi:10.1038/s41467-025-60129-1

Emerging Role of Blood-based Biomarkers in Sarcomas.

Shulman DS, Crompton BD. Emerging Role of Blood-based Biomarkers in Sarcomas. Hematology/oncology clinics of North America. 2025;39(4):679-692. doi:10.1016/j.hoc.2025.04.002

Durable response to CAR T is associated with elevated activation and clonotypic expansion of the cytotoxic native T cell repertoire.

Cheloni G, Karagkouni D, Pita-Juarez Y, et al. Durable response to CAR T is associated with elevated activation and clonotypic expansion of the cytotoxic native T cell repertoire. Nature communications. 2025;16(1):4819. doi:10.1038/s41467-025-59904-x

Whole-blood transcriptomic analysis reveals preoperative complement inhibitor deficiencies linked to postoperative delirium.

Graves OK, Kang J, Li H, et al. Whole-blood transcriptomic analysis reveals preoperative complement inhibitor deficiencies linked to postoperative delirium. Molecular psychiatry. 2025;30(10):4690-4699. doi:10.1038/s41380-025-03063-4

Pre-treatment untargeted cerebrospinal fluid metabolomic profiling in tuberculous meningitis uncovers pathways associated with mortality.

Le THN, van Abeelen KCJ, Ardiansyah E, et al. Pre-treatment untargeted cerebrospinal fluid metabolomic profiling in tuberculous meningitis uncovers pathways associated with mortality. Med (New York, N.Y.). 2025;6(9):100703. doi:10.1016/j.medj.2025.100703

Tegavivint triggers TECR-dependent nonapoptotic cancer cell death.

Leak L, Wang Z, Joseph AJ, et al. Tegavivint triggers TECR-dependent nonapoptotic cancer cell death. Nature chemical biology. 2025. doi:10.1038/s41589-025-01913-4

CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue.

Liu F, Shi H, Turner JD, et al. CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue. Annals of the rheumatic diseases. 2025;84(7):1151-1163. doi:10.1016/j.ard.2025.04.018