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Publications

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming.

Holman CD, Sakers AP, Calhoun RP, et al. Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming. eLife. 2024;12. doi:10.7554/eLife.87756

Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults.

Haslam DE, Liang L, Guo K, et al. Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults. Diabetologia. 2024. doi:10.1007/s00125-024-06169-6

Deep learning of left atrial structure and function provides link to atrial fibrillation risk.

Pirruccello JP, Di Achille P, Choi SH, et al. Deep learning of left atrial structure and function provides link to atrial fibrillation risk. Nature communications. 2024;15(1):4304. doi:10.1038/s41467-024-48229-w

Cell of origin epigenetic priming determines susceptibility to Tet2 mutation.

Schiroli G, Kartha V, Duarte FM, et al. Cell of origin epigenetic priming determines susceptibility to Tet2 mutation. Nature communications. 2024;15(1):4325. doi:10.1038/s41467-024-48508-6

Determinants of gastric cancer immune escape identified from non-coding immune-landscape quantitative trait loci.

Miliotis C, Ma Y, Katopodi XL, et al. Determinants of gastric cancer immune escape identified from non-coding immune-landscape quantitative trait loci. Nature communications. 2024;15(1):4319. doi:10.1038/s41467-024-48436-5

Elevated levels of IL-12/IL-23p40 in Nova Scotia Duck Tolling Retrievers with autoimmune disease and lymphoma.

Nilsson M, Kozyrev S V, Saellström S, et al. Elevated levels of IL-12/IL-23p40 in Nova Scotia Duck Tolling Retrievers with autoimmune disease and lymphoma. Scientific reports. 2024;14(1):11624. doi:10.1038/s41598-024-62265-y

Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.

Zheng X, Wu B, Liu Y, et al. Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development. Cell. 2024. doi:10.1016/j.cell.2024.04.050

Molecular and cellular context influences SCN8A variant function.

Vanoye CG, Abramova T V, DeKeyser JM, et al. Molecular and cellular context influences SCN8A variant function. JCI insight. 2024. doi:10.1172/jci.insight.177530

Reversibly Reactive Affinity Selection-Mass Spectrometry Enables Identification of Covalent Peptide Binders.

Zhang P, Ye X, Wang JCK, et al. Reversibly Reactive Affinity Selection-Mass Spectrometry Enables Identification of Covalent Peptide Binders. Journal of the American Chemical Society. 2024. doi:10.1021/jacs.4c05571

ProBac-seq, a bacterial single-cell RNA sequencing methodology using droplet microfluidics and large oligonucleotide probe sets.

Samanta P, Cooke SF, McNulty R, Hormoz S, Rosenthal A. ProBac-seq, a bacterial single-cell RNA sequencing methodology using droplet microfluidics and large oligonucleotide probe sets. Nature protocols. 2024. doi:10.1038/s41596-024-01002-1