Musunuru K, Grandinette S, Wang X, et al. Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease. The New England journal of medicine. 2025. doi:10.1056/NEJMoa2504747
Publications
Geady C, Bannon JJ, Reza S, et al. Measured intrapatient radiomic variability as a predictor of treatment response in multi-metastatic soft tissue sarcoma patients. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.04.11.25325700
Matuszek Ż, Arbab M, Kesavan M, et al. Base editing of trinucleotide repeats that cause Huntington’s disease and Friedreich’s ataxia reduces somatic repeat expansions in patient cells and in mice. Nature genetics. 2025. doi:10.1038/s41588-025-02172-8
Youssef N, Gurev S, Ghantous F, et al. Computationally designed proteins mimic antibody immune evasion in viral evolution. Immunity. 2025. doi:10.1016/j.immuni.2025.04.015
Smelyansky SR, Ma CW, Marando VM, et al. Exploiting thioether reactivity to label mycobacterial glycans. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(19):e2422185122. doi:10.1073/pnas.2422185122
Kannan S, Altae-Tran H, Zhu S, et al. Evolution-guided protein design of IscB for persistent epigenome editing in vivo. Nature biotechnology. 2025. doi:10.1038/s41587-025-02655-3
Witte IP, Lampe GD, Eitzinger S, et al. Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase. Science (New York, N.Y.). 2025;388(6748):eadt5199. doi:10.1126/science.adt5199
Paysan D, Radhakrishnan A, Zhang X, Shivashankar G V, Uhler C. Image2Reg: Linking chromatin images to gene regulation using genetic and chemical perturbation screens. Cell systems. 2025:101293. doi:10.1016/j.cels.2025.101293
Yamaguchi TN, Houlahan KE, Zhu H, et al. The Germline and Somatic Origins of Prostate Cancer Heterogeneity. Cancer discovery. 2025;15(5):988-1017. doi:10.1158/2159-8290.CD-23-0882
Alduhayh S, Laskar RS, Jiang X, et al. Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2025;34(5):722-736. doi:10.1158/1055-9965.EPI-24-0970