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Publications

Methyl-CODEC enables simultaneous methylation and duplex sequencing.

Liu R, Darbeheshti F, Walsh L, et al. Methyl-CODEC enables simultaneous methylation and duplex sequencing. Nucleic acids research. 2025;53(10). doi:10.1093/nar/gkaf482

Realizing the promise of genome-wide association studies for effector gene prediction.

Costanzo MC, Harris LW, Ji Y, McMahon A, Burtt NP, Flannick J. Realizing the promise of genome-wide association studies for effector gene prediction. Nature genetics. 2025. doi:10.1038/s41588-025-02210-5

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.

Akl CF, Andersen BM, Li Z, et al. Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity. Nature. 2025. doi:10.1038/s41586-025-08997-x

CoQ imbalance drives reverse electron transport to disrupt liver metabolism.

Goncalves RLS, Wang ZB, Riveros JK, et al. CoQ imbalance drives reverse electron transport to disrupt liver metabolism. Nature. 2025. doi:10.1038/s41586-025-09072-1

Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers.

Jaehnig EJ, Fernandez-Martinez A, Vashist TD, et al. Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers. Cell reports. Medicine. 2025:102154. doi:10.1016/j.xcrm.2025.102154

Association of distinct microbial and metabolic signatures with microscopic colitis.

Chen ASY, Kim H, Nzabarushimana E, et al. Association of distinct microbial and metabolic signatures with microscopic colitis. Nature communications. 2025;16(1):4644. doi:10.1038/s41467-025-59566-9

Polygenic Prediction of Peripheral Artery Disease and Major Adverse Limb Events.

Flores AM, Ruan Y, Misra A, et al. Polygenic Prediction of Peripheral Artery Disease and Major Adverse Limb Events. JAMA cardiology. 2025. doi:10.1001/jamacardio.2025.1182

Early Postoperative Minimal Residual Disease Detection with MAESTRO Is Associated with Recurrence and Worse Survival in Patients with Head and Neck Cancer.

Sim ES, Rhoades J, Xiong K, et al. Early Postoperative Minimal Residual Disease Detection with MAESTRO Is Associated with Recurrence and Worse Survival in Patients with Head and Neck Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025:OF1-OF9. doi:10.1158/1078-0432.CCR-25-0307

Direct Comparison of Alternative Blood-Based Approaches for Early Detection and Diagnosis of HPV-Associated Head and Neck Cancers.

Bryan ME, Aye L, Das D, et al. Direct Comparison of Alternative Blood-Based Approaches for Early Detection and Diagnosis of HPV-Associated Head and Neck Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025:OF1-OF11. doi:10.1158/1078-0432.CCR-24-2525

Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions.

Beck A, Gabler-Pamer L, Cruzeiro GAV, et al. Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions. Nature cancer. 2025. doi:10.1038/s43018-025-00964-9