ӳ��ý

Publications

Scalable automated reanalysis of genomic data in research and clinical rare disease cohorts.

Welland MJ, Ahlquist KD, De Fazio P, et al. Scalable automated reanalysis of genomic data in research and clinical rare disease cohorts. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.05.19.25327921

Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma.

Rämö JT, Gorman BR, Weng LC, et al. Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma. Nature communications. 2025;16(1):4127. doi:10.1038/s41467-025-58686-6

SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data.

Zhang D, Segerstolpe Å, Slyper M, et al. SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data. Genome biology. 2025;26(1):112. doi:10.1186/s13059-025-03573-y

Dissecting the immune landscape in pediatric high-grade glioma reveals cell state changes under therapeutic pressure.

LaBelle JJ, Haase RD, Beck A, et al. Dissecting the immune landscape in pediatric high-grade glioma reveals cell state changes under therapeutic pressure. Cell reports. Medicine. 2025;6(5):102095. doi:10.1016/j.xcrm.2025.102095

Orthogonal resistance mechanisms of classical- and induced-proximity inhibitors.

Merz M. Orthogonal resistance mechanisms of classical- and induced-proximity inhibitors. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.10.652755

Subcellular level spatial transcriptomics with PHOTON.

Rajachandran S, Xu Q, Cao Q, et al. Subcellular level spatial transcriptomics with PHOTON. Nature communications. 2025;16(1):4457. doi:10.1038/s41467-025-59801-3

Developing a general AI model for integrating diverse genomic modalities and comprehensive genomic knowledge.

Zhang Z, Bao X, Jiang L, et al. Developing a general AI model for integrating diverse genomic modalities and comprehensive genomic knowledge. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.08.652986

Deciphering the role of histone modifications in memory and exhausted CD8 T cells.

Huang H, Baxter AE, Zhang Z, et al. Deciphering the role of histone modifications in memory and exhausted CD8 T cells. Scientific reports. 2025;15(1):17359. doi:10.1038/s41598-025-99804-0

Ultrasmall chemogenetic tags with group-transfer ligands.

Vedagopuram S, Sindi S, Chaudhary S, et al. Ultrasmall chemogenetic tags with group-transfer ligands. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.10.653252

Phosphorylation-inducing molecules for regulating dynamic cellular processes.

Pergu R, Vedagopuram S, Kokkonda P, et al. Phosphorylation-inducing molecules for regulating dynamic cellular processes. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.10.652895