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Publications

Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro.

Nguyen AN, Kouyate TS, Ryff K, et al. Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro. Journal of innate immunity. 2025;17(1):288-301. doi:10.1159/000545432

Predicting expression-altering promoter mutations with deep learning.

Jaganathan K, Ersaro N, Novakovsky G, et al. Predicting expression-altering promoter mutations with deep learning. Science (New York, N.Y.). 2025;389(6760):eads7373. doi:10.1126/science.ads7373

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Jee YH, Wang Y, Jung KJ, et al. Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures. Nature communications. 2025;16(1):4935. doi:10.1038/s41467-025-59950-5

Trinucleotide substrates under pH-freeze-thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme.

Attwater J, Augustin TL, Curran JF, et al. Trinucleotide substrates under pH-freeze-thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme. Nature chemistry. 2025;17(7):1129-1137. doi:10.1038/s41557-025-01830-y

The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers.

Zajac N, Vlachos IS, Sajibu S, et al. The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers. Genome biology. 2025;26(1):145. doi:10.1186/s13059-025-03613-7

Clinical characteristics and outcomes of hospitalized patients with heart failure from the Japanese prospective registry.

Enzan N, Tohyama T, Watanabe T, et al. Clinical characteristics and outcomes of hospitalized patients with heart failure from the Japanese prospective registry. Journal of cardiology. 2025. doi:10.1016/j.jjcc.2025.05.015

Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes.

Medford AJ, Velimirovic M, Gefen Y, et al. Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes. Breast cancer research and treatment. 2025;212(3):437-447. doi:10.1007/s10549-025-07710-w

Predicting expression-altering promoter mutations with deep learning.

Jaganathan K, Ersaro N, Novakovsky G, et al. Predicting expression-altering promoter mutations with deep learning. Science (New York, N.Y.). 2025;389(6760):eads7373. doi:10.1126/science.ads7373

High resolution clonal architecture of hypomutated Wilms tumours.

Lee-Six H, Treger TD, Dave M, et al. High resolution clonal architecture of hypomutated Wilms tumours. Nature communications. 2025;16(1):4647. doi:10.1038/s41467-025-59854-4

Clinical characteristics and outcomes of hospitalized patients with heart failure from the Japanese prospective registry.

Enzan N, Tohyama T, Watanabe T, et al. Clinical characteristics and outcomes of hospitalized patients with heart failure from the Japanese prospective registry. Journal of cardiology. 2025. doi:10.1016/j.jjcc.2025.05.015