CRISPR-HAWK: Haplotype- and Variant-aware guide design toolkit for CRISPR-Cas. Kumbara A, Tognon M, Carone G, et al. CRISPR-HAWK: Haplotype- and Variant-aware guide design toolkit for CRISPR-Cas. bioRxiv : the preprint server for biology. 2025. doi:10.64898/2025.12.27.696698 PMCID PMC12767513 Read more
Individuals whose phenotype deviates from genetic expectation defined by common variation are enriched for rare damaging variants in genes that cause rare disease. Baya NA, Lassen FH, Hill B, et al. Individuals whose phenotype deviates from genetic expectation defined by common variation are enriched for rare damaging variants in genes that cause rare disease. medRxiv : the preprint server for health sciences. 2025. doi:10.64898/2025.12.30.25343229 PMCID PMC12772651 Read more
Learning cell dynamics with neural differential equations Vinyard ME, Rasmussen AW, Li R, Klein AM, Getz G. Learning cell dynamics with neural differential equations. Nature Machine Intelligence. 2025;7. doi:10.1038/s42256-025-01150-3 Read more
Fundamental errors in RNA velocity arising from the omission of cell growth. Shah V, Ming H, Cleary B. Fundamental errors in RNA velocity arising from the omission of cell growth. bioRxiv : the preprint server for biology. 2025. doi:10.64898/2025.12.18.695252 PMCID PMC12746066 Read more
Discrete interneuron subsets participate in GluN1/GluN3A excitatory glycine receptor (eGlyR)-mediated regulation of hippocampal network activity throughout development and evolution. Kim JH, Vlachos A, Mahadevan V, et al. Discrete interneuron subsets participate in GluN1/GluN3A excitatory glycine receptor (eGlyR)-mediated regulation of hippocampal network activity throughout development and evolution. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.24.678342 PMCID PMC12747254 Read more
Using Artificial Intelligence to Adjudicate Major Adverse Cardiovascular Events in Clinical Trials. Marti-Castellote PM, Badrouchi S, Claggett B, et al. Using Artificial Intelligence to Adjudicate Major Adverse Cardiovascular Events in Clinical Trials. Journal of the American College of Cardiology. 2025. doi:10.1016/j.jacc.2025.10.055 Read more
Artificial Intelligence to Extract Structured Details From Unstructured Medical Records in a Global Heart Failure Trial. Badrouchi S, Marti-Castellote PM, Foà A, et al. Artificial Intelligence to Extract Structured Details From Unstructured Medical Records in a Global Heart Failure Trial. JACC. Heart failure. 2025:102851. doi:10.1016/j.jchf.2025.102851 Read more
Learning Patient Similarity from Genomics for Precision Oncology. Shady M, Reardon B, Jiang S, et al. Learning Patient Similarity from Genomics for Precision Oncology. medRxiv : the preprint server for health sciences. 2025. doi:10.64898/2025.12.17.25342480 PMCID PMC12723981 Read more
Proteomic analysis identifies lipoprotein(a)-associated proteins linked to incident atherosclerotic cardiovascular disease events. Bellomo TR, Saadatagah S, Lee J, et al. Proteomic analysis identifies lipoprotein(a)-associated proteins linked to incident atherosclerotic cardiovascular disease events. medRxiv : the preprint server for health sciences. 2025. doi:10.64898/2025.12.16.25342337 PMCID PMC12723966 Read more
Benchmarking of duplex sequencing approaches to reveal somatic mutation landscapes. Zhang Y, Viswanadham V V, Andreopoulos M, et al. Benchmarking of duplex sequencing approaches to reveal somatic mutation landscapes. bioRxiv : the preprint server for biology. 2025. doi:10.64898/2025.12.12.692823 PMCID PMC12724167 Read more