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Publications

Engineered 3D immuno-glial-neurovascular human miBrain model.

Stanton AE, Bubnys A, Agbas E, et al. Engineered 3D immuno-glial-neurovascular human miBrain model. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(42):e2511596122. doi:10.1073/pnas.2511596122

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer.

Gong D, Liu R, Cui Y, et al. Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer. Science advances. 2025;11(42):eadx0632. doi:10.1126/sciadv.adx0632

Somatic mutations in STAG2 are associated with separated megakaryocyte nuclear lobes in myelodysplastic syndromes.

Wong WJ, Zon RL, Gibson CJ, et al. Somatic mutations in STAG2 are associated with separated megakaryocyte nuclear lobes in myelodysplastic syndromes. Blood advances. 2025;9(20):5283-5288. doi:10.1182/bloodadvances.2025016897

Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data.

Li R, Alberge JB, Keshavarzian T, et al. Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data. Briefings in bioinformatics. 2025;26(5). doi:10.1093/bib/bbaf516

ID2 suppresses multiple myeloma cell proliferation by repressing the activity of the transcription factor TCF3.

Fulciniti M, Yao Y, Perini T, et al. ID2 suppresses multiple myeloma cell proliferation by repressing the activity of the transcription factor TCF3. Blood cancer discovery. 2025. doi:10.1158/2643-3230.BCD-25-0048

Deep-learning-derived neuroimaging biomarkers of sarcopenia as predictors of outcome in endovascular thrombectomy in large vessel occlusion acute ischemic stroke.

Teo KSH, Tan BY, Teo YN, et al. Deep-learning-derived neuroimaging biomarkers of sarcopenia as predictors of outcome in endovascular thrombectomy in large vessel occlusion acute ischemic stroke. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. 2025:15910199251386116. doi:10.1177/15910199251386116

Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state.

Chiasson-MacKenzie C, Zhang Y, O’Loughlin E, et al. Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2024.08.30.610360

PMCID

PMC11398422

The specificity and structure of DNA crosslinking by the gut bacterial genotoxin colibactin.

Carlson ES, Haslecker R, Lecchi C, et al. The specificity and structure of DNA crosslinking by the gut bacterial genotoxin colibactin. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.05.26.655968

PMCID

PMC12154741

Distinguishing diet- and microbe-derived metabolites in the human gut.

Tanes C, Hu W, Friedman E, et al. Distinguishing diet- and microbe-derived metabolites in the human gut. Microbiome. 2025;13(1):206. doi:10.1186/s40168-025-02258-9

SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations.

Ma Y, Xu H, Li Y, et al. SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations. Genome biology. 2025;26(1):356. doi:10.1186/s13059-025-03827-9