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Publications

Targeting glutamine catabolism suppresses eosinophil expansion and activation to alleviate allergic airway inflammation.

Du X, Wang Y, Huang J, et al. Targeting glutamine catabolism suppresses eosinophil expansion and activation to alleviate allergic airway inflammation. Biochemical pharmacology. 2025:117443. doi:10.1016/j.bcp.2025.117443

scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution.

Hingerl JC, Martens LD, Karollus A, et al. scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution. Nature methods. 2025. doi:10.1038/s41592-025-02854-5

Tissue and cellular spatiotemporal dynamics in colon aging.

Daly AC, Cambuli F, Äijö T, et al. Tissue and cellular spatiotemporal dynamics in colon aging. Nature biotechnology. 2025. doi:10.1038/s41587-025-02830-6

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function.

Asadollahi R, Ahmad A, Boonsawat P, et al. Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function. Nature genetics. 2025. doi:10.1038/s41588-025-02361-5

Mapping Plasmodium transitions and interactions in the Anopheles female.

Yan Y, Verzier LH, Cheung E, et al. Mapping Plasmodium transitions and interactions in the Anopheles female. Nature. 2025. doi:10.1038/s41586-025-09653-0

Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma.

Nopsopon T, Cabrera-Perez J, Lee PY, et al. Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma. Respiratory research. 2025;26(1):291. doi:10.1186/s12931-025-03373-9

An ingestible capsule for luminance-based diagnosis of mesenteric ischemia.

Chen J, Alexiev A, Sergnese A, et al. An ingestible capsule for luminance-based diagnosis of mesenteric ischemia. Science robotics. 2025;10(107):eadx1367. doi:10.1126/scirobotics.adx1367

Kcnn4/KCa3.1 inhibition blunts polycystic kidney disease progression in mouse models.

Yao G, Kurbegovic A, Parrot C, et al. Kcnn4/KCa3.1 inhibition blunts polycystic kidney disease progression in mouse models. JCI insight. 2025;10(20). doi:10.1172/jci.insight.191311

Combining Polygenic Risk With LDL, CRP, and Lp(a) to Predict Coronary Artery Disease: UK Biobank Study.

Khetarpal SA, Shi Z, Goyal A, et al. Combining Polygenic Risk With LDL, CRP, and Lp(a) to Predict Coronary Artery Disease: UK Biobank Study. Journal of the American College of Cardiology. 2025. doi:10.1016/j.jacc.2025.08.069

Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial.

Shimano KA, Grimes AB, Kaicker S, et al. Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial. JAMA. 2025. doi:10.1001/jama.2025.18168