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Publications

Safety and implementation of a phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns.

Violari A, Otwombe K, Hahn W, et al. Safety and implementation of a phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.10.15.24315548

K-mer analysis of long-read alignment pileups for structural variant genotyping.

English AC, Cunial F, Metcalf GA, Gibbs RA, Sedlazeck FJ. K-mer analysis of long-read alignment pileups for structural variant genotyping. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.22.619642

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ, Dilly J, Liu S, et al. Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.22.618529

Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis.

Jones MG, Sun D, Min KHJ, et al. Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.21.619529

A framework for target discovery in rare cancers.

Li B, Sadagopan A, Li J, et al. A framework for target discovery in rare cancers. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.24.620074

Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape.

Muir DF, Asper GPR, Notin P, et al. Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.23.619915

Site of breast cancer metastasis is independent of single nutrient levels.

Abbott KL, Subudhi S, Ferreira R, et al. Site of breast cancer metastasis is independent of single nutrient levels. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.24.616714

Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project).

Ramirez-Diaz AM, Diaz-Zuluaga AM, Stroud RE, et al. Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project). medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.10.02.24314732

Exploring psychotic symptoms among substance-naïve individuals and recent abstainers without a psychosis diagnosis: A cross-country study across Kenya, Uganda, Ethiopia, and South Africa.

Kisiang’ani IB, Aden M, Mwangi HR, et al. Exploring psychotic symptoms among substance-naïve individuals and recent abstainers without a psychosis diagnosis: A cross-country study across Kenya, Uganda, Ethiopia, and South Africa. Psychiatry research. 2024;342:116253. doi:10.1016/j.psychres.2024.116253

Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.

Jena KK, Mambu J, Boehmer D, et al. Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair. Cell. 2024. doi:10.1016/j.cell.2024.10.010