Ancestry-specific performance of variant effect predictors in clinical variant classification. Hoffing R, Zeiberg D, Stenton SL, et al. Ancestry-specific performance of variant effect predictors in clinical variant classification. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.02.14.705914 PMCID PMC12934965 Read more
A Scalable Design for Proximity-Inducing Molecules. Karaj E, Venkatarangan V, Sindi SH, et al. A Scalable Design for Proximity-Inducing Molecules. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.02.20.706349 PMCID PMC12934950 Read more
Mechanistic machine learning enables interpretable and generalizable prediction of prime editing outcomes. Hsu A, Chen PJ, Li AH, et al. Mechanistic machine learning enables interpretable and generalizable prediction of prime editing outcomes. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.02.20.706353 PMCID PMC12934823 Read more
Mapping spatially organized molecular and genetic signatures of schizophrenia across multiple scales in human prefrontal cortex. Kwon SH, Guo B, Fang C, et al. Mapping spatially organized molecular and genetic signatures of schizophrenia across multiple scales in human prefrontal cortex. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.02.16.706214 PMCID PMC12934622 Read more
A Soft-Robotic Biomimetic Benchtop Model for Esophageal Motility Simulation. Kilroy S, Patankar NA, Chan WW, Traverso G, O’Cearbhaill ED. A Soft-Robotic Biomimetic Benchtop Model for Esophageal Motility Simulation. Nature communications. 2026. doi:10.1038/s41467-026-70260-2 Read more
Multimodal framework for the joint analysis of single-cell RNA and T cell receptor sequencing data predicts T cell response to cancer immunotherapy. He C, Amodio M, Ashenberg O, Wucherpfennig KW, Xavier RJ, Uhler C. Multimodal framework for the joint analysis of single-cell RNA and T cell receptor sequencing data predicts T cell response to cancer immunotherapy. Nature communications. 2026. doi:10.1038/s41467-026-70505-0 Read more
Defining the vascular niche of human adipose tissue across metabolic states. AlZaim I, Hassan MN, Schröter M, et al. Defining the vascular niche of human adipose tissue across metabolic states. Nature metabolism. 2026. doi:10.1038/s42255-026-01475-2 Read more
Feeder-free yet still naïve: improved method for capturing human pluripotent stem cells. Yagi M, Hochedlinger K. Feeder-free yet still naïve: improved method for capturing human pluripotent stem cells. The EMBO journal. 2026. doi:10.1038/s44318-026-00713-3 Read more
Pursuing the elusive biosignature for suicide: a decennial update. Barzilay R, Sudol K, Daskalakis NP, Dupont MB, Oquendo MA. Pursuing the elusive biosignature for suicide: a decennial update. Molecular psychiatry. 2026. doi:10.1038/s41380-026-03507-5 Read more
A clinical environment simulator for dynamic AI evaluation. Luo L, Kim SE, Zhang X, et al. A clinical environment simulator for dynamic AI evaluation. Nature medicine. 2026. doi:10.1038/s41591-026-04252-6 Read more