Publications

A rare splice-site variant in TNNT2: the need for ancestral diversity in genomic reference data sets.

Butters A, Thomson K, Harrington F, et al. A rare splice-site variant in TNNT2: the need for ancestral diversity in genomic reference data sets. European heart journal. 2025. doi:10.1093/eurheartj/ehaf001

SplitFusion enables ultrasensitive gene fusion detection and reveals fusion variant-associated tumor heterogeneity.

Bian W, Zhang B, Song Z, et al. SplitFusion enables ultrasensitive gene fusion detection and reveals fusion variant-associated tumor heterogeneity. Patterns (New York, N.Y.). 2025;6(2):101174. doi:10.1016/j.patter.2025.101174

Heterovalent Click Reactions on DNA Origami.

Knappe GA, Gorman J, Bigley AN, Harvey SP, Bathe M. Heterovalent Click Reactions on DNA Origami. Bioconjugate chemistry. 2025. doi:10.1021/acs.bioconjchem.4c00552

The link between traumatic experiences and health in late life: challenges and opportunities for US-based longitudinal aging cohorts.

Murchland AR, Koenen KC, Hayes-Larson E. The link between traumatic experiences and health in late life: challenges and opportunities for US-based longitudinal aging cohorts. American journal of epidemiology. 2025;194(3):565-572. doi:10.1093/aje/kwae278

TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes.

Martin P, Szkop KJ, Robert F, et al. TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes. Brain : a journal of neurology. 2025. doi:10.1093/brain/awaf081

Dietary Nut and Legume Intake and Risk of Crohn's Disease and Ulcerative Colitis.

Lopes EW, Yu Z, Walsh SE, et al. Dietary Nut and Legume Intake and Risk of Crohn’s Disease and Ulcerative Colitis. Inflammatory bowel diseases. 2025. doi:10.1093/ibd/izaf032

Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.

Henry A, Mo X, Finan C, et al. Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes. Nature genetics. 2025. doi:10.1038/s41588-024-02064-3

Decomposed interaction testing improves detection of genetic modifiers of the relationship of dietary omega-3 fatty acid intake and its plasma biomarkers with hsCRP in the UK Biobank.

Westerman KE, Patel CJ, Meigs JB, Chasman DI, Manning AK. Decomposed interaction testing improves detection of genetic modifiers of the relationship of dietary omega-3 fatty acid intake and its plasma biomarkers with hsCRP in the UK Biobank. Genes & nutrition. 2025;20(1):3. doi:10.1186/s12263-025-00765-w

Genomic Taxometric Analysis of Negative Emotionality and Major Depressive Disorder Highlights a Gradient of Genetic Differentiation across the Severity Spectrum.

Ennis GW, Mallard TT, de la Fuente J, Williams CM, Schwaba T, Tucker-Drob EM. Genomic Taxometric Analysis of Negative Emotionality and Major Depressive Disorder Highlights a Gradient of Genetic Differentiation across the Severity Spectrum. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.01.30.25321336

Identification of Hub Genes Involved in Early-onset Schizophrenia: From Genetic Susceptibility to Predicted Regulated Gene Expression.

Jen Y, Yu SL, Hsiao PC, et al. Identification of Hub Genes Involved in Early-onset Schizophrenia: From Genetic Susceptibility to Predicted Regulated Gene Expression. Research square. 2025. doi:10.21203/rs.3.rs-5833160/v1