ӳ��ý

Publications

Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma.

Aprati TJ, Day CP, Lee D, et al. Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.01.24.633441

Refining the cis-regulatory grammar learned by sequence-to-activity models by increasing model resolution.

Chandra NA, Hu Y, Buenrostro JD, Mostafavi S, Sasse A. Refining the cis-regulatory grammar learned by sequence-to-activity models by increasing model resolution. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.01.24.634804

Cell signaling pathways discovery from multi-modal data.

He C, Simpson C, Cossentino I, et al. Cell signaling pathways discovery from multi-modal data. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.02.06.636961

Distinguishing new from persistent infections at the strain level using longitudinal genotyping data.

Nickols WA, Schwabl P, Niangaly A, Murphy SC, Crompton PD, Neafsey DE. Distinguishing new from persistent infections at the strain level using longitudinal genotyping data. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.02.06.636982

Discovery of Chirally-dependent Protein -2-Hydroxyglutarylation by D2HG and L2HG.

Zhang Z, Liu YK, Luo Z, et al. Discovery of Chirally-dependent Protein -2-Hydroxyglutarylation by D2HG and L2HG. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.01.24.634716

Heterogeneous constraint and adaptation across the malaria parasite life cycle.

Perkins SA, Neafsey DE, Early AM. Heterogeneous constraint and adaptation across the malaria parasite life cycle. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.02.11.636054

Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.

He X, Wang Q, Cheng X, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043

HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.

Jiang Q, Braun DA, Clauser KR, et al. HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy. Cell. 2025. doi:10.1016/j.cell.2025.01.046

PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation.

Fang R, Vallius T, Zhang A, et al. PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation. Laboratory investigation; a journal of technical methods and pathology. 2025:104123. doi:10.1016/j.labinv.2025.104123

Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics.

Johri S, Bi K, Titchen BM, et al. Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics. Nature communications. 2025;16(1):2090. doi:10.1038/s41467-025-57377-6