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Publications

Use of patient-derived organotypic tumor spheroids for testing of viral vector gene therapy in combination with checkpoint blockade.

Domingues ACM, de Oliveira SB, Tessarollo NG, et al. Use of patient-derived organotypic tumor spheroids for testing of viral vector gene therapy in combination with checkpoint blockade. Molecular therapy. Oncology. 2025;33(1):200942. doi:10.1016/j.omton.2025.200942

Distinct rates of VUS reclassification are observed when subclassifying VUS by evidence level.

Bennett G, Karbassi I, Chen W, et al. Distinct rates of VUS reclassification are observed when subclassifying VUS by evidence level. Genetics in medicine : official journal of the American College of Medical Genetics. 2025:101400. doi:10.1016/j.gim.2025.101400

Impact of Social Determinants of Health on Cardiovascular Disease.

Bazoukis G, Loscalzo J, Hall JL, Bollepalli SC, Singh JP, Armoundas AA. Impact of Social Determinants of Health on Cardiovascular Disease. Journal of the American Heart Association. 2025;14(5):e039031. doi:10.1161/JAHA.124.039031

Predicting future risk of developing cognitive impairment using ambulatory sleep EEG: Integrating univariate analysis and multivariate information theory approach.

Haghayegh S, Herzog R, Bennett DA, et al. Predicting future risk of developing cognitive impairment using ambulatory sleep EEG: Integrating univariate analysis and multivariate information theory approach. Journal of Alzheimer’s disease : JAD. 2025:13872877251319742. doi:10.1177/13872877251319742

Predicting Milk Flow Behavior in Human Lactating Breast: An Integrated Machine Learning and Computational Fluid Dynamics Approach.

Olapojoye AO, Zaheri S, Nosratinia A, Hassanipour F. Predicting Milk Flow Behavior in Human Lactating Breast: An Integrated Machine Learning and Computational Fluid Dynamics Approach. Journal of biomechanical engineering. 2025:1-16. doi:10.1115/1.4068077

Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes.

Hwang J, Likasitwatanakul P, Deshmukh SK, et al. Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025;31(5):936-948. doi:10.1158/1078-0432.CCR-24-3471

Prevalence and disease risks for male and female sex chromosome trisomies: a registry-based phenome-wide association study in 1.5 million participants of MVP, FinnGen, and UK Biobank.

Davis SM, Liu A, Teerlink CC, et al. Prevalence and disease risks for male and female sex chromosome trisomies: a registry-based phenome-wide association study in 1.5 million participants of MVP, FinnGen, and UK Biobank. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.01.31.25321488

N-terminal modification of Histone H3 inhibits H3K27M-mediated loss of H3K27 trimethylation.

Poux N, Zhang DF, Kebede AF, et al. N-terminal modification of Histone H3 inhibits H3K27M-mediated loss of H3K27 trimethylation. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.01.24.634760

Intraspecies associations from strain-rich metagenome samples.

Qu EB, Baker JS, Markey L, et al. Intraspecies associations from strain-rich metagenome samples. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.02.07.636498

BESTDR: Bayesian quantification of mechanism-specific drug response in cell culture.

McDonald TO, Bruno S, Roney JP, Zervantonakis IK, Michor F. BESTDR: Bayesian quantification of mechanism-specific drug response in cell culture. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.02.05.636681