Clonal Hematopoiesis Instructs Maladaptive Tissue Repair to Promote Fibrosis. Li D, Viñado AC, Garcia-Olloqui P, et al. Clonal Hematopoiesis Instructs Maladaptive Tissue Repair to Promote Fibrosis. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.24.710438 PMCID PMC13041955 Read more
A uniquely leptin sensitive hypothalamic neuron population limits hyperphagia and weight gain in diet-induced obesity. Belmont-Rausch DM, Kapel BS, Tomlinson AJ, et al. A uniquely leptin sensitive hypothalamic neuron population limits hyperphagia and weight gain in diet-induced obesity. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.26.714161 PMCID PMC13041805 Read more
Rare coding and noncoding variants map 1,342 diseases and biomarkers in 490,549 whole genomes. Yuan Y, Guan Y, Feng Y, et al. Rare coding and noncoding variants map 1,342 diseases and biomarkers in 490,549 whole genomes. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.24.26349148 PMCID PMC13042129 Read more
, a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss. Liedtke D, Rak K, Schrode KM, et al. , a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.27.26349271 PMCID PMC13060437 Read more
Integrating 730,947 exome sequences with clinical literature improves gene discovery. Guez J, Goodrich JK, Moldovan MA, et al. Integrating 730,947 exome sequences with clinical literature improves gene discovery. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.23.26349081 PMCID PMC13042128 Read more
Effects of Genetically-Proxied Antihypertensive Drug Targets on Preeclampsia and Birth Weight. Ardissino M, Morley AP, Richards EMF, et al. Effects of Genetically-Proxied Antihypertensive Drug Targets on Preeclampsia and Birth Weight. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.17.26346752 PMCID PMC13042138 Read more
Inter-individual variation of cellular and gene-expression properties of the human striatum. Burger S, Yoo O, Nemesh J, et al. Inter-individual variation of cellular and gene-expression properties of the human striatum. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.20.713160 PMCID PMC13042060 Read more
Epigenome editing of human hematopoietic stem cells enables sustained and reversible thrombosis prevention. Ye T, Xu W, Barrachina MN, et al. Epigenome editing of human hematopoietic stem cells enables sustained and reversible thrombosis prevention. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.27.714536 PMCID PMC13042045 Read more
Hidden immune memory niches in inflammatory skin diseases. Steele L, Foster AR, Roberts K, et al. Hidden immune memory niches in inflammatory skin diseases. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.20.713219 PMCID PMC13041989 Read more
Integrating Long-Read Structural Variant Analysis with single-nucleus RNA-seq to Elucidate Gene Expression Effects in Disease. Kim K, Lin Z, Simmons SK, et al. Integrating Long-Read Structural Variant Analysis with single-nucleus RNA-seq to Elucidate Gene Expression Effects in Disease. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.20.713192 PMCID PMC13041997 Read more