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Publications

Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro.

Nguyen AN, Kouyate TS, Ryff K, et al. Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro. Journal of innate immunity. 2025;17(1):288-301. doi:10.1159/000545432

Early establishment and life course stability of sex biases in the human brain transcriptome.

Benoit-Pilven C, Asteljoki J V, Leinonen JT, Karjalainen J, Daly MJ, Tukiainen T. Early establishment and life course stability of sex biases in the human brain transcriptome. Cell genomics. 2025;5(7):100890. doi:10.1016/j.xgen.2025.100890

Were bed bugs the first urban pest insect? Genome-wide patterns of bed bug demography mirror global human expansion.

Miles LS, Verrelli BC, Adams R, et al. Were bed bugs the first urban pest insect? Genome-wide patterns of bed bug demography mirror global human expansion. Biology letters. 2025;21(5):20250061. doi:10.1098/rsbl.2025.0061

Twin Study Provides Heritability Estimates for 2321 Plasma Proteins and Assesses Missing SNP Heritability.

Drouard G, Hagenbeek FA, Ollikainen M, et al. Twin Study Provides Heritability Estimates for 2321 Plasma Proteins and Assesses Missing SNP Heritability. Journal of proteome research. 2025;24(6):2689-2697. doi:10.1021/acs.jproteome.4c00971

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.

Jee YH, Wang Y, Jung KJ, et al. Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures. Nature communications. 2025;16(1):4935. doi:10.1038/s41467-025-59950-5

Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy.

Borot F, Humbert O, Ehmsen JT, et al. Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy. Nature communications. 2025;16(1):4899. doi:10.1038/s41467-025-59713-2

Trinucleotide substrates under pH-freeze-thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme.

Attwater J, Augustin TL, Curran JF, et al. Trinucleotide substrates under pH-freeze-thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme. Nature chemistry. 2025;17(7):1129-1137. doi:10.1038/s41557-025-01830-y

The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers.

Zajac N, Vlachos IS, Sajibu S, et al. The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers. Genome biology. 2025;26(1):145. doi:10.1186/s13059-025-03613-7

Presence of Coliforms and Reduced Water Quality in the Second Biggest Reservoir in São Paulo, Brazil.

Nascimento A, Fernandes LA, de Biagi CAO, Marcondes MA, Sanabani SS. Presence of Coliforms and Reduced Water Quality in the Second Biggest Reservoir in São Paulo, Brazil. Life (Basel, Switzerland). 2025;15(5). doi:10.3390/life15050729

A comprehensive evaluation of candidate genetic polymorphisms in a large histologically characterized MASLD cohort using a novel framework.

Hakim A, Lin KH, Schwantes-An TH, et al. A comprehensive evaluation of candidate genetic polymorphisms in a large histologically characterized MASLD cohort using a novel framework. Hepatology communications. 2025;9(6). doi:10.1097/HC9.0000000000000728