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Publications

Matrix prior for data transfer between single cell data types in latent Dirichlet allocation.

Min A, Durham T, Gevirtzman L, Noble WS. Matrix prior for data transfer between single cell data types in latent Dirichlet allocation. PLoS computational biology. 2023;19(5):e1011049. doi:10.1371/journal.pcbi.1011049

A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma.

Alladina J, Smith NP, Kooistra T, et al. A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma. Science immunology. 2023;8(83):eabq6352. doi:10.1126/sciimmunol.abq6352

Evolution of the crustal phosphorus reservoir.

Walton CR, Hao J, Huang F, et al. Evolution of the crustal phosphorus reservoir. Science advances. 2023;9(18):eade6923. doi:10.1126/sciadv.ade6923

Genetic events associated with venetoclax resistance in CLL identified by whole exome sequencing of patient samples.

Khalsa JK, Cha J, Utro F, et al. Genetic events associated with venetoclax resistance in CLL identified by whole exome sequencing of patient samples. Blood. 2023. doi:10.1182/blood.2022016600

Single-cell analysis reveals inflammatory interactions driving macular degeneration.

Kuchroo M, DiStasio M, Song E, et al. Single-cell analysis reveals inflammatory interactions driving macular degeneration. Nature communications. 2023;14(1):2589. doi:10.1038/s41467-023-37025-7

The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.

Huerta-Chagoya A, Schroeder P, Mandla R, et al. The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. Diabetologia. 2023. doi:10.1007/s00125-023-05912-9

Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly.

Adamson RJ, Payne C, Bartual SG, Mazitschek R, Bullock AN. Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly. Free radical biology & medicine. 2023. doi:10.1016/j.freeradbiomed.2023.04.021

A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories.

Placido D, Yuan B, Hjaltelin JX, et al. A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories. Nature medicine. 2023. doi:10.1038/s41591-023-02332-5

Catch me if you can: capturing microbial community transformation by extracellular DNA using Hi-C sequencing.

Calderón-Franco D, van Loosdrecht MCM, Abeel T, Weissbrodt DG. Catch me if you can: capturing microbial community transformation by extracellular DNA using Hi-C sequencing. Antonie van Leeuwenhoek. 2023. doi:10.1007/s10482-023-01834-z

Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments.

Goel VY, Huseyin MK, Hansen AS. Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments. Nature genetics. 2023. doi:10.1038/s41588-023-01391-1