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Publications

Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease.

Fahed AC, Wang M, Patel AP, et al. Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease. JAMA Netw Open. 2022;5(3):e222687. doi:10.1001/jamanetworkopen.2022.2687

Deep learning-enabled assessment of cardiac allograft rejection from endomyocardial biopsies.

Lipkova J, Chen TY, Lu MY, et al. Deep learning-enabled assessment of cardiac allograft rejection from endomyocardial biopsies. Nat Med. 2022;28(3):575-582. doi:10.1038/s41591-022-01709-2

Establishing the role of the gut microbiota in susceptibility to recurrent urinary tract infections.

Worby CJ, Olson BS, Dodson KW, Earl AM, Hultgren SJ. Establishing the role of the gut microbiota in susceptibility to recurrent urinary tract infections. J Clin Invest. 2022;132(5). doi:10.1172/JCI158497

Total synthesis of himastatin.

D’Angelo KA, Schissel CK, Pentelute BL, Movassaghi M. Total synthesis of himastatin. Science. 2022;375(6583):894-899. doi:10.1126/science.abm6509

Population genetics and microevolution of clinical Candida glabrata reveals recombinant sequence types and hyper-variation within mitochondrial genomes, virulence genes and drug-targets.

Helmstetter N, Chybowska AD, Delaney C, et al. Population genetics and microevolution of clinical Candida glabrata reveals recombinant sequence types and hyper-variation within mitochondrial genomes, virulence genes and drug-targets. Genetics. 2022. doi:10.1093/genetics/iyac031

Ancient DNA and deep population structure in sub-Saharan African foragers.

Lipson M, Sawchuk EA, Thompson JC, et al. Ancient DNA and deep population structure in sub-Saharan African foragers. Nature. 2022. doi:10.1038/s41586-022-04430-9

Batf-mediated epigenetic control of effector CD8 T cell differentiation.

Tsao HW, Kaminski J, Kurachi M, et al. Batf-mediated epigenetic control of effector CD8 T cell differentiation. Sci Immunol. 2022;7(68):eabi4919. doi:10.1126/sciimmunol.abi4919

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank.

Jurgens SJ, Choi SH, Morrill VN, et al. Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank. Nat Genet. 2022. doi:10.1038/s41588-021-01011-w

Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate.

Lagattuta KA, Kang JB, Nathan A, et al. Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate. Nat Immunol. 2022. doi:10.1038/s41590-022-01129-x

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness.

Obermeyer F, Jankowiak M, Barkas N, et al. Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness. medRxiv. 2022. doi:10.1101/2021.09.07.21263228