Publications

Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut.

Lynch JP, González-Prieto C, Reeves AZ, et al. Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut. Cell host & microbe. 2023;31(4):634-649.e8. doi:10.1016/j.chom.2023.03.007

The origins and functional effects of postzygotic mutations throughout the human life span.

Rockweiler NB, Ramu A, Nagirnaja L, et al. The origins and functional effects of postzygotic mutations throughout the human life span. Science (New York, N.Y.). 2023;380(6641):eabn7113. doi:10.1126/science.abn7113

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.

Shrine N, Izquierdo AG, Chen J, et al. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics. 2023;55(3):410-422. doi:10.1038/s41588-023-01314-0

Produces a pH-Responsive Lipid Immunogen.

Kwon J, Bae M, Szamosvári D, et al. Produces a pH-Responsive Lipid Immunogen. Journal of the American Chemical Society. 2023;145(13):7071-7074. doi:10.1021/jacs.3c00250

On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis.

Key FM, Khadka VD, Romo-González C, et al. On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis. Cell host & microbe. 2023;31(4):593-603.e7. doi:10.1016/j.chom.2023.03.009

Stratified Genetic Analysis Reveals Sex Differences In MPO-ANCA-associated Vasculitis.

Ekman D, Sennblad B, Knight A, et al. Stratified Genetic Analysis Reveals Sex Differences In MPO-ANCA-associated Vasculitis. Rheumatology (Oxford, England). 2023. doi:10.1093/rheumatology/kead152

Cue: a deep-learning framework for structural variant discovery and genotyping.

Popic V, Rohlicek C, Cunial F, et al. Cue: a deep-learning framework for structural variant discovery and genotyping. Nature methods. 2023;20(4):559-568. doi:10.1038/s41592-023-01799-x

Bi-allelic variants in INTS11 are associated with a complex neurological disorder.

Tepe B, Macke EL, Niceta M, et al. Bi-allelic variants in INTS11 are associated with a complex neurological disorder. American journal of human genetics. 2023;110(5):774-789. doi:10.1016/j.ajhg.2023.03.012

Adjusting for common variant polygenic scores improves yield in rare variant association analyses.

Jurgens SJ, Pirruccello JP, Choi SH, et al. Adjusting for common variant polygenic scores improves yield in rare variant association analyses. Nature genetics. 2023;55(4):544-548. doi:10.1038/s41588-023-01342-w

Genomes of four Streptomyces strains reveal insights into putative new species and pathogenicity of scab-causing organisms.

Henao L, Zade RSH, Restrepo S, Husserl J, Abeel T. Genomes of four Streptomyces strains reveal insights into putative new species and pathogenicity of scab-causing organisms. BMC genomics. 2023;24(1):143. doi:10.1186/s12864-023-09190-y

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Publications

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