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Publications

Parental compliance and reasons for COVID-19 Vaccination among American children.

Sehgal NKR, Rader B, Gertz A, Astley CM, Brownstein JS. Parental compliance and reasons for COVID-19 Vaccination among American children. PLOS digital health. 2023;2(4):e0000147. doi:10.1371/journal.pdig.0000147

A genome-wide optical pooled screen reveals regulators of cellular antiviral responses.

Carlson RJ, Leiken MD, Guna A, Hacohen N, Blainey PC. A genome-wide optical pooled screen reveals regulators of cellular antiviral responses. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(16):e2210623120. doi:10.1073/pnas.2210623120

Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells.

Park SM, Miyamoto DK, Han GYQ, et al. Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells. Cancer cell. 2023;41(4):726-739.e11. doi:10.1016/j.ccell.2023.02.010

Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer.

Nimgaonkar V, Krishna V, Krishna V, et al. Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer. Cell reports. Medicine. 2023;4(4):101013. doi:10.1016/j.xcrm.2023.101013

Linoleic acid potentiates CD8 T cell metabolic fitness and antitumor immunity.

Lauson CBN, Tiberti S, Corsetto PA, et al. Linoleic acid potentiates CD8 T cell metabolic fitness and antitumor immunity. Cell metabolism. 2023;35(4):633-650.e9. doi:10.1016/j.cmet.2023.02.013

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.

Weinstock JS, Gopakumar J, Burugula BB, et al. Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. Nature. 2023;616(7958):755-763. doi:10.1038/s41586-023-05806-1

Fractal dynamics of individual mitochondrial oscillators measure local inter-mitochondrial coupling.

Kurz FT, Aon MA, Schlemmer HP, Jende JME, O’Rourke B, Armoundas AA. Fractal dynamics of individual mitochondrial oscillators measure local inter-mitochondrial coupling. Biophysical journal. 2023;122(8):1459-1469. doi:10.1016/j.bpj.2023.03.011

Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors.

Lu W, Fan M, Ji W, et al. Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors. Journal of medicinal chemistry. 2023;66(7):4617-4632. doi:10.1021/acs.jmedchem.2c01548

Fetal Hemoglobin Regulation in Beta-Thalassemia.

Lu HY, Orkin SH, Sankaran VG. Fetal Hemoglobin Regulation in Beta-Thalassemia. Hematology/oncology clinics of North America. 2023;37(2):301-312. doi:10.1016/j.hoc.2022.12.002

ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma.

Eichhoff OM, Stoffel CI, Käsler J, et al. ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma. Cancer research. 2023;83(7):1128-1146. doi:10.1158/0008-5472.CAN-22-1826