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Publications

On the limits of fitting complex models of population history to -statistics.

Maier R, Flegontov P, Flegontova O, Isildak U, Changmai P, Reich D. On the limits of fitting complex models of population history to -statistics. eLife. 2023;12. doi:10.7554/eLife.85492

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.

Costanzo MC, von Grotthuss M, Massung J, et al. The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits. Cell metabolism. 2023;35(4):695-710.e6. doi:10.1016/j.cmet.2023.03.001

NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-Space: Reaching out to Clinicians.

Hall JL, Honeycutt S, Gonzalez N, et al. NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-Space: Reaching out to Clinicians. Circulation. Genomic and precision medicine. 2023:e003936. doi:10.1161/CIRCGEN.122.003936

Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study.

Kim MS, Song M, Kim S, et al. Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study. Obesity (Silver Spring, Md.). 2023. doi:10.1002/oby.23722

Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice.

Quan YZ, Wei W, Ergin V, et al. Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(17):e2215253120. doi:10.1073/pnas.2215253120

Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration.

Neel D V, Basu H, Gunner G, et al. Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration. Neuron. 2023;111(8):1222-1240.e9. doi:10.1016/j.neuron.2023.02.019

IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation.

Goers L, Kim K, Stedman TC, et al. IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(15):e2218469120. doi:10.1073/pnas.2218469120

U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes.

Mimoso CA, Adelman K. U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes. Molecular cell. 2023;83(8):1264-1279.e10. doi:10.1016/j.molcel.2023.03.002

ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas.

Jiang B, Weinstock DM, Donovan KA, et al. ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas. Cell chemical biology. 2023;30(4):383-393.e6. doi:10.1016/j.chembiol.2023.03.007

A hypothesis for robust polarization vision: an example from the Australian imperial blue butterfly, Jalmenus evagoras.

Childers RAR, Bernard GD, Huang H, et al. A hypothesis for robust polarization vision: an example from the Australian imperial blue butterfly, Jalmenus evagoras. The Journal of experimental biology. 2023;226(7). doi:10.1242/jeb.244515