Fahed AC, Wang M, Homburger JR, et al. Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions. Nat Commun. 2020;11(1):3635. doi:10.1038/s41467-020-17374-3
Publications
Cohen KA, Stott KE, Munsamy V, Manson AL, Earl AM, Pym AS. Evidence for Expanding the Role of Streptomycin in the Management of Drug-Resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2020;64(9). doi:10.1128/AAC.00860-20
Lerchenmüller C, Rabolli CP, Yeri A, et al. CITED4 Protects Against Adverse Remodeling in Response to Physiological and Pathological Stress. Circ Res. 2020;127(5):631-646. doi:10.1161/CIRCRESAHA.119.315881
Heyne HO, Baez-Nieto D, Iqbal S, et al. Predicting functional effects of missense variants in voltage-gated sodium and calcium channels. Sci Transl Med. 2020;12(556). doi:10.1126/scitranslmed.aay6848
Bis JC, Jian X, Kunkle BW, et al. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2020;25(8):1859-1875. doi:10.1038/s41380-018-0112-7
Sherva R, Gross A, Mukherjee S, et al. Genome-wide association study of rate of cognitive decline in Alzheimer’s disease patients identifies novel genes and pathways. Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2020;16(8):1134-1145. doi:10.1002/alz.12106
PMCID
PMC7924136
Glastonbury CA, Pulit SL, Honecker J, et al. Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits. PLoS computational biology. 2020;16(8):e1008044. doi:10.1371/journal.pcbi.1008044
Oguri Y, Shinoda K, Kim H, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. 2020;182(3):563-577.e20. doi:10.1016/j.cell.2020.06.021
Siriwardena SU, Godage DNPM, Shoba VM, et al. Phosphorylation-Inducing Chimeric Small Molecules. Journal of the American Chemical Society. 2020;142(33):14052-14057. doi:10.1021/jacs.0c05537
Lim D, Sreekanth V, Cox KJ, et al. Engineering designer beta cells with a CRISPR-Cas9 conjugation platform. Nature communications. 2020;11(1):4043. doi:10.1038/s41467-020-17725-0