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Publications

Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing.

Joung J, Ladha A, Saito M, et al. Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing. N Engl J Med. 2020. doi:10.1056/NEJMc2026172

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency.

Gupta M, Concepcion CP, Fahey CG, et al. BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency. Cancer Res. 2020;80(18):3841-3854. doi:10.1158/0008-5472.CAN-20-1744

RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting.

Han S, Zhao BS, Myers SA, Carr SA, He C, Ting AY. RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting. Proc Natl Acad Sci U S A. 2020;117(36):22068-22079. doi:10.1073/pnas.2006617117

Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35

Atack TC, Raymond DD, Blomquist CA, et al. Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35. ACS Medicinal Chemistry Letters. 2020;11(11):2131-2138.

Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35

Atack TC, Raymond DD, Blomquist CA, et al. Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35. ACS Medicinal Chemistry Letters. 2020;11(11):2131-2138.

Genomic Profiling of Prostate Cancers from Men with African and European Ancestry.

Koga Y, Song H, Chalmers ZR, et al. Genomic Profiling of Prostate Cancers from Men with African and European Ancestry. Clin Cancer Res. 2020;26(17):4651-4660. doi:10.1158/1078-0432.CCR-19-4112

Cell type-specific genetic regulation of gene expression across human tissues.

Kim-Hellmuth S. Cell type-specific genetic regulation of gene expression across human tissues. Science (New York, N.Y.). 2020;369(6509). doi:10.1126/science.aaz8528

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.

Li X, Li Z, Zhou H, et al. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature genetics. 2020;52(9):969-983. doi:10.1038/s41588-020-0676-4

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion.

Zou Y, Henry WS, Ricq EL, et al. Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. Nature. 2020;585(7826):603-608. doi:10.1038/s41586-020-2732-8

Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.

McFarland JM, Paolella BR, Warren A, et al. Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action. Nat Commun. 2020;11(1):4296. doi:10.1038/s41467-020-17440-w