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Publications

Genomic diversity of the human pathogen Paracoccidioides across the South American continent.

Teixeira M de M, Cattana ME, Matute DR, et al. Genomic diversity of the human pathogen Paracoccidioides across the South American continent. Fungal Genet Biol. 2020;140:103395. doi:10.1016/j.fgb.2020.103395

Liability threshold modeling of case-control status and family history of disease increases association power.

Hujoel MLA, Gazal S, Loh PR, Patterson N, Price AL. Liability threshold modeling of case-control status and family history of disease increases association power. Nat Genet. 2020. doi:10.1038/s41588-020-0613-6

A Deep Learning Approach to Antibiotic Discovery.

Stokes JM, Yang K, Swanson K, et al. A Deep Learning Approach to Antibiotic Discovery. Cell. 2020;181(2):475-483. doi:10.1016/j.cell.2020.04.001

Progress in Understanding Ferroptosis and Challenges in Its Targeting for Therapeutic Benefit.

Zou Y, Schreiber SL. Progress in Understanding Ferroptosis and Challenges in Its Targeting for Therapeutic Benefit. Cell Chem Biol. 2020;27(4):463-471. doi:10.1016/j.chembiol.2020.03.015

Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab.

Kim N, Cho D, Kim H, et al. Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab. Int J Cancer. 2020;146(8):2194-2200. doi:10.1002/ijc.32499

Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.

Marchesini M, Gherli A, Montanaro A, et al. Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol. 2020. doi:10.1016/j.chembiol.2020.04.002

Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence.

Lett TA, Vogel BO, Ripke S, et al. Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence. Cereb Cortex. 2020;30(4):2707-2718. doi:10.1093/cercor/bhz270

Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors.

Zhang Z, Mäkinen N, Kasai Y, et al. Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors. Genes Chromosomes Cancer. 2020. doi:10.1002/gcc.22850

Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae.

Ernst CM, Braxton JR, Rodriguez-Osorio CA, et al. Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae. Nat Med. 2020. doi:10.1038/s41591-020-0825-4

Design and analysis of CRISPR-Cas experiments.

Hanna RE, Doench JG. Design and analysis of CRISPR-Cas experiments. Nat Biotechnol. 2020. doi:10.1038/s41587-020-0490-7