Publications

Dual CRISPRi-seq for genome-wide genetic interaction studies identifies key genes involved in the pneumococcal cell cycle.

Dénéréaz J, Eray E, Jana B, et al. Dual CRISPRi-seq for genome-wide genetic interaction studies identifies key genes involved in the pneumococcal cell cycle. Cell systems. 2025:101408. doi:10.1016/j.cels.2025.101408

Enhancing randomized clinical trials with digital twins.

Akbarialiabad H, Pasdar A, Murrell DF, et al. Enhancing randomized clinical trials with digital twins. NPJ systems biology and applications. 2025;11(1):110. doi:10.1038/s41540-025-00592-0

Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health.

Jawinski P, Forstbach H, Kirsten H, et al. Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health. Nature aging. 2025. doi:10.1038/s43587-025-00962-7

Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer.

Luo J, Chen Z, Qiao Y, et al. Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer. Nature genetics. 2025. doi:10.1038/s41588-025-02336-6

Predicting drug responses of unseen cell types through transfer learning with foundation models.

Wang Y, Liu X, Fan Y, et al. Predicting drug responses of unseen cell types through transfer learning with foundation models. Nature computational science. 2025. doi:10.1038/s43588-025-00887-6

The immunology of brain tumors.

Bunse L, Bunse T, Kilian M, Quintana FJ, Platten M. The immunology of brain tumors. Science immunology. 2025;10(112):eads0449. doi:10.1126/sciimmunol.ads0449

Anti-Inflammatory Therapies for Atherosclerotic Stroke Prevention.

Georgakis MK, Melton P, Živković L, Kopczak A, Katsanos AH. Anti-Inflammatory Therapies for Atherosclerotic Stroke Prevention. Neurology. 2025;105(9):e214214. doi:10.1212/WNL.0000000000214214

Fibrinolytic Therapy for Thromboembolic Diseases: Approved Indications and Future Directions.

Rashedi S, Leyva H, Hamade N, et al. Fibrinolytic Therapy for Thromboembolic Diseases: Approved Indications and Future Directions. Journal of the American College of Cardiology. 2025;86(14):1065-1087. doi:10.1016/j.jacc.2025.07.061

Hybrid BAG-seq: DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples.

Li S, Alexander J, Kendall J, et al. Hybrid BAG-seq: DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples. Genome biology. 2025;26(1):314. doi:10.1186/s13059-025-03790-5

Pancreatic cancer risk prediction using deep sequential modeling of longitudinal diagnostic and medication records.

Zheng C, Khan A, Ritter D, et al. Pancreatic cancer risk prediction using deep sequential modeling of longitudinal diagnostic and medication records. Cell reports. Medicine. 2025;6(9):102359. doi:10.1016/j.xcrm.2025.102359

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Publications

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