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Publications

HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors.

Abu-Remaileh M, Stransky LA, Bhalerao N, et al. HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.09.09.675147

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene.

Eder M, Moene CJI, Dauban L, et al. Functional maps of a genomic locus reveal confinement of an enhancer by its target gene. Science (New York, N.Y.). 2025;389(6766):eads6552. doi:10.1126/science.ads6552

Cell-free DNA as a complementary marker of therapeutic futility in adenoid cystic carcinoma.

Blocka J, Lim K, Stuart H, et al. Cell-free DNA as a complementary marker of therapeutic futility in adenoid cystic carcinoma. Oral oncology. 2025;169:107688. doi:10.1016/j.oraloncology.2025.107688

A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity.

Kaas M, Dinesen SB, Ahlgreen O, et al. A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity. Molecular psychiatry. 2025. doi:10.1038/s41380-025-03242-3

The OASIS Consortium: Integrating Multi-Omics Technologies to Transform Chemical Safety Assessment.

Rouquié D, Bender A, Cheah J, et al. The OASIS Consortium: Integrating Multi-Omics Technologies to Transform Chemical Safety Assessment. Toxicological sciences : an official journal of the Society of Toxicology. 2025. doi:10.1093/toxsci/kfaf128

Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program.

Wang N, Ockerman FP, Zhou LY, et al. Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program. American journal of human genetics. 2025. doi:10.1016/j.ajhg.2025.08.022

The global, regional, and national burden attributable to low bone mineral density, 1990-2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021.

The global, regional, and national burden attributable to low bone mineral density, 1990-2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021. The Lancet. Rheumatology. 2025. doi:10.1016/S2665-9913(25)00105-5

colorSV: Long-range Somatic Structural Variation Calling from Matched Tumor-normal Co-assembly Graphs.

Le MK, Qin Q, Li H. colorSV: Long-range Somatic Structural Variation Calling from Matched Tumor-normal Co-assembly Graphs. Genomics, proteomics & bioinformatics. 2025. doi:10.1093/gpbjnl/qzaf082

Scalable Tracking of Symptoms in the Electronic Health Record using Large Language Models in Patients with Central Nervous System Cancers Undergoing Therapy.

Rhee JY, Tentor Z, Sounack T, et al. Scalable Tracking of Symptoms in the Electronic Health Record using Large Language Models in Patients with Central Nervous System Cancers Undergoing Therapy. Neuro-oncology. 2025. doi:10.1093/neuonc/noaf223

The endogenous T cell landscape is reshaped by CAR-T cell therapy and predicts treatment response in multiple myeloma.

Frede J, Poller JC, Shi K, et al. The endogenous T cell landscape is reshaped by CAR-T cell therapy and predicts treatment response in multiple myeloma. Leukemia. 2025. doi:10.1038/s41375-025-02766-5