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Publications

Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses.

Xu H, Ding J, Porter CBM, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 2019;51(4):696-708.e9. doi:10.1016/j.immuni.2019.09.004

Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses.

Wallrapp A, Burkett PR, Riesenfeld SJ, et al. Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses. Immunity. 2019;51(4):709-723.e6. doi:10.1016/j.immuni.2019.09.005

A nuclease-polymerase chain reaction enables amplification of probes used for capture-based DNA target enrichment.

Leong KW, Yu F, Adalsteinsson VA, et al. A nuclease-polymerase chain reaction enables amplification of probes used for capture-based DNA target enrichment. Nucleic Acids Res. 2019. doi:10.1093/nar/gkz870

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Nievergelt CM, Maihofer AX, Klengel T, et al. International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat Commun. 2019;10(1):4558. doi:10.1038/s41467-019-12576-w

Programmable Inhibition and Detection of RNA Viruses Using Cas13.

Freije CA, Myhrvold C, Boehm CK, et al. Programmable Inhibition and Detection of RNA Viruses Using Cas13. Mol Cell. 2019. doi:10.1016/j.molcel.2019.09.013

Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS.

Papanastasiou M, Mullahoo J, DeRuff KC, et al. Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS. Mol Cell Proteomics. 2019;18(10):2089-2098. doi:10.1074/mcp.RA119.001325

Population imaging of neural activity in awake behaving mice.

Piatkevich KD, Bensussen S, Tseng HA, et al. Population imaging of neural activity in awake behaving mice. Nature. 2019;574(7778):413-417. doi:10.1038/s41586-019-1641-1

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program.

HuBMAP Consortium. The human body at cellular resolution: the NIH Human Biomolecular Atlas Program. Nature. 2019;574(7777):187-192. doi:10.1038/s41586-019-1629-x

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.

Sulahian R, Kwon JJ, Walsh KH, et al. Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers. Cell Rep. 2019;29(1):118-134.e8. doi:10.1016/j.celrep.2019.08.090

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.

Christian S, Merz C, Evans L, et al. The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia. 2019;33(10):2403-2415. doi:10.1038/s41375-019-0461-5