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Publications

QuantTB - a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data.

Anyansi C, Keo A, Walker BJ, et al. QuantTB - a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data. BMC Genomics. 2020;21(1):80. doi:10.1186/s12864-020-6486-3

Microscaled proteogenomic methods for precision oncology.

Satpathy S, Jaehnig EJ, Krug K, et al. Microscaled proteogenomic methods for precision oncology. Nat Commun. 2020;11(1):532. doi:10.1038/s41467-020-14381-2

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.

Wertz MH, Mitchem MR, Pineda S, et al. Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity. Neuron. 2020. doi:10.1016/j.neuron.2020.01.004

Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits.

Ghoshal A, Uygun DS, Yang L, et al. Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Transl Psychiatry. 2020;10(1):29. doi:10.1038/s41398-020-0685-1

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase.

Catania S, Dumesic PA, Pimentel H, et al. Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase. Cell. 2020;180(2):263-277.e20. doi:10.1016/j.cell.2019.12.012

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators.

Li J, Han S, Li H, et al. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Cell. 2020;180(2):373-386.e15. doi:10.1016/j.cell.2019.12.029

Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

Nusinow DP, Szpyt J, Ghandi M, et al. Quantitative Proteomics of the Cancer Cell Line Encyclopedia. Cell. 2020;180(2):387-402.e16. doi:10.1016/j.cell.2019.12.023

Protein Structure from Experimental Evolution.

Stiffler MA, Poelwijk FJ, Brock KP, et al. Protein Structure from Experimental Evolution. Cell Syst. 2020;10(1):15-24.e5. doi:10.1016/j.cels.2019.11.008

Ocular Dominance Plasticity in Binocular Primary Visual Cortex Does Not Require C1q.

Welsh CA, Stephany CÉ, Sapp RW, Stevens B. Ocular Dominance Plasticity in Binocular Primary Visual Cortex Does Not Require C1q. J Neurosci. 2020;40(4):769-783. doi:10.1523/JNEUROSCI.1011-19.2019

Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization.

Bolan PO, Zviran A, Brenan L, et al. Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization. Cell Syst. 2020;10(1):52-65.e7. doi:10.1016/j.cels.2019.10.002