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Publications

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin.

Miller EL, Hargreaves DC, Kadoch C, et al. TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nat Struct Mol Biol. 2017;24(4):344-352. doi:10.1038/nsmb.3384

Biallelic mutations in human DCC cause developmental split-brain syndrome.

Jamuar SS, Schmitz-Abe K, D’Gama AM, et al. Biallelic mutations in human DCC cause developmental split-brain syndrome. Nat Genet. 2017;49(4):606-612. doi:10.1038/ng.3804

Olig1 is required for noggin-induced neonatal myelin repair.

Sabo JK, Heine V, Silbereis JC, Schirmer L, Levison SW, Rowitch DH. Olig1 is required for noggin-induced neonatal myelin repair. Ann Neurol. 2017;81(4):560-571. doi:10.1002/ana.24907

Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples.

Kosmicki JA, Samocha KE, Howrigan DP, et al. Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples. Nat Genet. 2017;49(4):504-510. doi:10.1038/ng.3789

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

Kim B, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions. Nat Biotechnol. 2017;35(4):371-376. doi:10.1038/nbt.3803

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.

Gierahn TM, Wadsworth MH, Hughes TK, et al. Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput. Nat Methods. 2017;14(4):395-398. doi:10.1038/nmeth.4179

miR-149 and miR-29c as candidates for bipolar disorder biomarkers.

Choi JL, Kao PF, Itriago E, et al. miR-149 and miR-29c as candidates for bipolar disorder biomarkers. Am J Med Genet B Neuropsychiatr Genet. 2017;174(3):315-323. doi:10.1002/ajmg.b.32518

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.

Schuetze KB, Stratton MS, Blakeslee WW, et al. Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts. J Pharmacol Exp Ther. 2017;361(1):140-150. doi:10.1124/jpet.116.237701

Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation.

Karwacz K, Miraldi ER, Pokrovskii M, et al. Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation. Nat Immunol. 2017;18(4):412-421. doi:10.1038/ni.3683

Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom.

Chheda H, Palta P, Pirinen M, et al. Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom. Eur J Hum Genet. 2017;25(4):477-484. doi:10.1038/ejhg.2016.205