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Publications

Evolving health care through personal genomics.

Rehm HL. Evolving health care through personal genomics. Nat Rev Genet. 2017;18(4):259-267. doi:10.1038/nrg.2016.162

Building a lineage from single cells: genetic techniques for cell lineage tracking.

Woodworth MB, Girskis KM, Walsh CA. Building a lineage from single cells: genetic techniques for cell lineage tracking. Nat Rev Genet. 2017;18(4):230-244. doi:10.1038/nrg.2016.159

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

Venteicher AS, Tirosh I, Hebert C, et al. Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science. 2017;355(6332). doi:10.1126/science.aai8478

Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers.

Ng S, March S, Galstian A, et al. Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers. Sci Rep. 2017;7:45424. doi:10.1038/srep45424

LACTB is a tumour suppressor that modulates lipid metabolism and cell state.

Keckesova Z, Donaher JL, De Cock J, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543(7647):681-686. doi:10.1038/nature21408

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.

Botella L, Vaubourgeix J, Livny J, Schnappinger D. Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Nat Commun. 2017;8:14731. doi:10.1038/ncomms14731

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.

Huang K lin, Li S, Mertins P, et al. Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun. 2017;8:14864. doi:10.1038/ncomms14864

Genetic effects influencing risk for major depressive disorder in China and Europe.

Bigdeli TB, Ripke S, Peterson RE, et al. Genetic effects influencing risk for major depressive disorder in China and Europe. Transl Psychiatry. 2017;7(3):e1074. doi:10.1038/tp.2016.292

Neuroprotective Functions for the Histone Deacetylase SIRT6.

Kaluski S, Portillo M, Besnard A, et al. Neuroprotective Functions for the Histone Deacetylase SIRT6. Cell Rep. 2017;18(13):3052-3062. doi:10.1016/j.celrep.2017.03.008

A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.

Zhou J, Tien AC, Alberta JA, et al. A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2. Cell Rep. 2017;18(13):3167-3177. doi:10.1016/j.celrep.2017.03.003