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Publications

Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data.

Costanzo MC, Akolkar B, Claussnitzer M, et al. Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data. Diabetes. 2025. doi:10.2337/db25-0042

Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma.

Li K, Tolman N, Segrè A V, et al. Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma. eLife. 2025;14. doi:10.7554/eLife.105576

Visceral Fat Quantified by a Fully Automated Deep-Learning Algorithm and Risk of Incident and Recurrent Diverticulitis.

Ha J, Bridge CP, Andriole KP, et al. Visceral Fat Quantified by a Fully Automated Deep-Learning Algorithm and Risk of Incident and Recurrent Diverticulitis. Diseases of the colon and rectum. 2025. doi:10.1097/DCR.0000000000003677

Multisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in male mice with Down Syndrome.

Islam MR, Jackson B, Naomi MT, et al. Multisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in male mice with Down Syndrome. PloS one. 2025;20(4):e0317428. doi:10.1371/journal.pone.0317428

Editorial Expression of Concern: A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.

Johannessen CM, Johnson LA, Piccioni F, et al. Editorial Expression of Concern: A melanocyte lineage program confers resistance to MAP kinase pathway inhibition. Nature. 2025. doi:10.1038/s41586-025-09027-6

InSituCor: exploring spatially correlated genes conditional on the cell type landscape.

Danaher P, McGuire D, Wu L, et al. InSituCor: exploring spatially correlated genes conditional on the cell type landscape. Genome biology. 2025;26(1):105. doi:10.1186/s13059-025-03554-1

Childhood HDL-C and Adult ASCVD: Mechanistic Insights and Preventive Implications.

Ahmadizar F, Natarajan P, Paruchuri K. Childhood HDL-C and Adult ASCVD: Mechanistic Insights and Preventive Implications. European journal of preventive cardiology. 2025. doi:10.1093/eurjpc/zwaf265

Bridging intensity is associated with impaired hematopoietic recovery following BCMA CAR-T therapy for multiple myeloma.

Frenking JH, Zhou X, Rejeski K, et al. Bridging intensity is associated with impaired hematopoietic recovery following BCMA CAR-T therapy for multiple myeloma. Blood advances. 2025. doi:10.1182/bloodadvances.2024015732

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts.

Luckett AM, Oram RA, Deutsch AJ, et al. Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts. Diabetes care. 2025. doi:10.2337/dc25-0142

Association Between Sleep Duration and Cognitive Frailty in Older Chinese Adults: Prospective Cohort Study.

Cai R, Chao J, Gao C, Gao L, Hu K, Li P. Association Between Sleep Duration and Cognitive Frailty in Older Chinese Adults: Prospective Cohort Study. JMIR aging. 2025;8:e65183. doi:10.2196/65183