Publications

Neuroproteasomes regulate endogenous tau paired helical filament formation in an APOE genotype- and age-dependent manner.

Paradise V, Konrad-Vicario KD, Nguyen C, et al. Neuroproteasomes regulate endogenous tau paired helical filament formation in an APOE genotype- and age-dependent manner. Nature neuroscience. 2026. doi:10.1038/s41593-026-02297-x

Pnky lncRNA secondary structure maps identify functional regions that control neurogenesis in neural stem cells.

Saha P, Patel S, Tsao LH, et al. Pnky lncRNA secondary structure maps identify functional regions that control neurogenesis in neural stem cells. Cell reports. 2026;45(6):117451. doi:10.1016/j.celrep.2026.117451

Machine learning cross-platform proteomic imputation enables protein quality scoring and replication of epidemiological associations.

Li L, Alaa A, Tan Y, et al. Machine learning cross-platform proteomic imputation enables protein quality scoring and replication of epidemiological associations. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.05.05.723059

PMCID

PMC13174605

Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma.

Agius MP, Song C, Liu Q, et al. Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma. Nature chemical biology. 2026. doi:10.1038/s41589-026-02228-8

Cancer vaccines: comprehensive review.

Clifford RE, Manu N, Yang Q, et al. Cancer vaccines: comprehensive review. BJS open. 2026;10(3). doi:10.1093/bjsopen/zrag041

Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial.

Merriam P, Morrow JJ, Mazzola E, et al. Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial. Nature medicine. 2026. doi:10.1038/s41591-026-04376-9

Circulating Tumor DNA in Early Breast Cancer: A Review.

Schlam I, Tolaney SM, Lin NU, Parsons H, Morganti S. Circulating Tumor DNA in Early Breast Cancer: A Review. JAMA oncology. 2026. doi:10.1001/jamaoncol.2026.1465

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease.

Dinesh D, Morgan XC, Jensen J, et al. Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson’s Disease. Annals of neurology. 2026. doi:10.1002/ana.78243

The Evidence Aggregator: AI reasoning applied to rare disease diagnostics.

Twede H, Pais L, Bryen S, et al. The Evidence Aggregator: AI reasoning applied to rare disease diagnostics. Genetics in medicine : official journal of the American College of Medical Genetics. 2026:102612. doi:10.1016/j.gim.2026.102612

Long-lasting gut microbiome and fecal metabolome alterations after colorectal adenoma removal and their relationship to colorectal cancer.

Nogal A, Wang K, Thompson KN, et al. Long-lasting gut microbiome and fecal metabolome alterations after colorectal adenoma removal and their relationship to colorectal cancer. Cell host & microbe. 2026. doi:10.1016/j.chom.2026.05.001

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Publications

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