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Publications

Schizophyllum commune has an extensive and functional alternative splicing repertoire.

Gehrmann T, Pelkmans JF, Lugones LG, Wösten HAB, Abeel T, Reinders MJT. Schizophyllum commune has an extensive and functional alternative splicing repertoire. Sci Rep. 2016;6:33640. doi:10.1038/srep33640

Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles.

Aleem SU, Georghiou G, Kleiner RE, et al. Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chem Biol. 2016;23(9):1103-12. doi:10.1016/j.chembiol.2016.07.017

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Sykes DB, Kfoury YS, Mercier FE, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. 2016;167(1):171-186.e15. doi:10.1016/j.cell.2016.08.057

Adaptive radiation by waves of gene transfer leads to fine-scale resource partitioning in marine microbes.

Hehemann JH, Arevalo P, Datta MS, et al. Adaptive radiation by waves of gene transfer leads to fine-scale resource partitioning in marine microbes. Nat Commun. 2016;7:12860. doi:10.1038/ncomms12860

Prescription medication changes following direct-to-consumer personal genomic testing: findings from the Impact of Personal Genomics (PGen) Study.

Carere DA, VanderWeele TJ, Vassy JL, et al. Prescription medication changes following direct-to-consumer personal genomic testing: findings from the Impact of Personal Genomics (PGen) Study. Genet Med. 2016. doi:10.1038/gim.2016.141

Portable, On-Demand Biomolecular Manufacturing.

Pardee K, Slomovic S, Nguyen PQ, et al. Portable, On-Demand Biomolecular Manufacturing. Cell. 2016;167(1):248-259.e12. doi:10.1016/j.cell.2016.09.013

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, et al. High-throughput discovery of novel developmental phenotypes. Nature. 2016;537(7621):508-514. doi:10.1038/nature19356

Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits.

McAvoy KM, Scobie KN, Berger S, et al. Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits. Neuron. 2016;91(6):1356-73. doi:10.1016/j.neuron.2016.08.009

The apo-structure of the leucine sensor Sestrin2 is still elusive.

Saxton RA, Knockenhauer KE, Schwartz TU, Sabatini DM. The apo-structure of the leucine sensor Sestrin2 is still elusive. Sci Signal. 2016;9(446):ra92. doi:10.1126/scisignal.aah4497

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials.

Livingstone KM, Celis-Morales C, Papandonatos GD, et al. FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials. BMJ. 2016;354:i4707. doi:10.1136/bmj.i4707