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Publications

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution.

Corces R, Buenrostro JD, Wu B, et al. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nat Genet. 2016;48(10):1193-203. doi:10.1038/ng.3646

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes.

Ruderfer DM, Hamamsy T, Lek M, et al. Patterns of genic intolerance of rare copy number variation in 59,898 human exomes. Nat Genet. 2016;48(10):1107-11. doi:10.1038/ng.3638

High-resolution interrogation of functional elements in the noncoding genome.

Sanjana NE, Wright J, Zheng K, et al. High-resolution interrogation of functional elements in the noncoding genome. Science. 2016;353(6307):1545-1549. doi:10.1126/science.aaf7613

Observation of a new channel, the production of CH3, in the abstraction reaction of OH radicals with acetaldehyde.

Howes NUM, Lockhart JPA, Blitz MA, et al. Observation of a new channel, the production of CH3, in the abstraction reaction of OH radicals with acetaldehyde. Phys Chem Chem Phys. 2016;18(38):26423-26433. doi:10.1039/c6cp03970g

Genomic Analysis of Viral Outbreaks.

Wohl S, Schaffner SF, Sabeti PC. Genomic Analysis of Viral Outbreaks. Annu Rev Virol. 2016;3(1):173-195. doi:10.1146/annurev-virology-110615-035747

Erratum to: Comparative genomics and transcriptomics of Pichia pastoris.

Love KR, Shah KA, Whittaker CA, et al. Erratum to: Comparative genomics and transcriptomics of Pichia pastoris. BMC Genomics. 2016;17(1):762. doi:10.1186/s12864-016-3109-0

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

Rosenbluh J, Mercer J, Shrestha Y, et al. Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers. Cell Syst. 2016;3(3):302-316.e4. doi:10.1016/j.cels.2016.09.001

52 Genetic Loci Influencing Myocardial Mass.

van der Harst P, van Setten J, Verweij N, et al. 52 Genetic Loci Influencing Myocardial Mass. J Am Coll Cardiol. 2016;68(13):1435-48. doi:10.1016/j.jacc.2016.07.729

Morphometricity as a measure of the neuroanatomical signature of a trait.

Sabuncu MR, Ge T, Holmes AJ, et al. Morphometricity as a measure of the neuroanatomical signature of a trait. Proc Natl Acad Sci U S A. 2016;113(39):E5749-56. doi:10.1073/pnas.1604378113

Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors.

Jain PK, Ramanan V, Schepers AG, et al. Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors. Angew Chem Int Ed Engl. 2016;55(40):12440-4. doi:10.1002/anie.201606123