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Publications

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth.

Cox AG, Hwang KL, Brown KK, et al. Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nat Cell Biol. 2016;18(8):886-96. doi:10.1038/ncb3389

APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage.

Phuah CL, Raffeld MR, Ayres AM, et al. APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage. Neurol Genet. 2016;2(4):e81. doi:10.1212/NXG.0000000000000081

The importance of serine metabolism in cancer.

Mattaini KR, Sullivan MR, Heiden MGV. The importance of serine metabolism in cancer. J Cell Biol. 2016;214(3):249-57. doi:10.1083/jcb.201604085

Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax.

Hupalo DN, Luo Z, Melnikov A, et al. Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax. Nat Genet. 2016;48(8):953-8. doi:10.1038/ng.3588

Loss of vhl in the zebrafish pronephros recapitulates early stages of human clear cell renal cell carcinoma.

Noonan HR, Metelo AM, Kamei CN, Peterson RT, Drummond IA, Iliopoulos O. Loss of vhl in the zebrafish pronephros recapitulates early stages of human clear cell renal cell carcinoma. Dis Model Mech. 2016;9(8):873-84. doi:10.1242/dmm.024380

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units.

Uzel SGM, Platt RJ, Subramanian V, et al. Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units. Sci Adv. 2016;2(8):e1501429. doi:10.1126/sciadv.1501429

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.

Giannikou K, Malinowska IA, Pugh TJ, et al. Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development. PLoS Genet. 2016;12(8):e1006242. doi:10.1371/journal.pgen.1006242

A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study.

Christophersen IE, Yin X, Larson MG, et al. A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study. Am Heart J. 2016;178:45-54. doi:10.1016/j.ahj.2016.05.004

Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

Chan G, White CC, Winn PA, et al. Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci. Neurol Genet. 2016;2(4):e90. doi:10.1212/NXG.0000000000000090

A highly multiplexed and sensitive RNA-seq protocol for simultaneous analysis of host and pathogen transcriptomes.

Avraham R, Haseley N, Fan A, Bloom-Ackermann Z, Livny J, Hung DT. A highly multiplexed and sensitive RNA-seq protocol for simultaneous analysis of host and pathogen transcriptomes. Nat Protoc. 2016;11(8):1477-91. doi:10.1038/nprot.2016.090