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Publications

Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population.

Xu Q, Wu X, Li M, et al. Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population. Pharmacogenomics J. 2016;16(4):357-65. doi:10.1038/tpj.2015.61

Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology.

Adams SL, Tilton K, Kozubek JA, Seshadri S, Delalle I. Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology. J Neuropathol Exp Neurol. 2016;75(8):779-790. doi:10.1093/jnen/nlw056

DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets.

Hanaford AR, Archer TC, Price A, et al. DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. Clin Cancer Res. 2016;22(15):3903-14. doi:10.1158/1078-0432.CCR-15-3011

Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance.

Cancer Target Discovery and Development Network. Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance. Mol Cancer Res. 2016;14(8):675-82. doi:10.1158/1541-7786.MCR-16-0090

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Hou L, Bergen SE, Akula N, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet. 2016;25(15):3383-3394. doi:10.1093/hmg/ddw181

Hydrophobic CDR3 residues promote the development of self-reactive T cells.

Stadinski BD, Shekhar K, Gómez-Touriño I, et al. Hydrophobic CDR3 residues promote the development of self-reactive T cells. Nat Immunol. 2016;17(8):946-55. doi:10.1038/ni.3491

Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury.

Subramanian B, Sun H, Yan P, et al. Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury. Kidney Int. 2016;90(2):363-72. doi:10.1016/j.kint.2016.04.020

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi.

Li Y, Oosting M, Deelen P, et al. Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi. Nat Med. 2016;22(8):952-60. doi:10.1038/nm.4139

Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study.

Peloso GM, Lange LA, Varga TV, et al. Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study. Circ Cardiovasc Genet. 2016;9(4):368-74. doi:10.1161/CIRCGENETICS.116.001410

Uncovering the Role of the Methylome in Dementia and Neurodegeneration.

Klein HU, De Jager PL. Uncovering the Role of the Methylome in Dementia and Neurodegeneration. Trends Mol Med. 2016;22(8):687-700. doi:10.1016/j.molmed.2016.06.008