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Publications

A sterol-binding pocket in iRhom1 underlies paralog-specific regulation of the sheddase ADAM17.

Lu F, Zhao H, Dai Y, Lee CH, Freeman M. A sterol-binding pocket in iRhom1 underlies paralog-specific regulation of the sheddase ADAM17. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.04.28.721421

PMCID

PMC13142363

MarkerMatch: a Proximity-Based Probe-Matching Algorithm for Joint Analysis of Copy-Number Variants from Different Genotyping Arrays.

Ivankovic F, Yu D, Shen J, et al. MarkerMatch: a Proximity-Based Probe-Matching Algorithm for Joint Analysis of Copy-Number Variants from Different Genotyping Arrays. Bioinformatics (Oxford, England). 2026. doi:10.1093/bioinformatics/btag341

In Vitro Massively Parallel Screening of Human Regulatory Elements Involved in Postcranial Skeletal Development for Differential Activity Compared to Chimpanzee.

Okamoto AS, Coveney CR, Ganapathee DS, Capellini TD. In Vitro Massively Parallel Screening of Human Regulatory Elements Involved in Postcranial Skeletal Development for Differential Activity Compared to Chimpanzee. Genome biology and evolution. 2026;18(5). doi:10.1093/gbe/evag121

PMCID

PMC13198024

Genetic variants affect diurnal glucose levels throughout the day.

Sinnott-Armstrong N, Strausz S, Urpa L, et al. Genetic variants affect diurnal glucose levels throughout the day. Nature communications. 2026. doi:10.1038/s41467-026-72432-6

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines.

Jena KK, Qu P, Baracco L, et al. A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines. Nature immunology. 2026. doi:10.1038/s41590-026-02517-3

Immune development in early life.

Palma P, Farber DL, Konnikova L, Levy O. Immune development in early life. Nature immunology. 2026. doi:10.1038/s41590-026-02523-5

Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress.

Mazzola MC, Zhao T, Kiem A, et al. Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress. Science advances. 2026;12(21):eadz7896. doi:10.1126/sciadv.adz7896

Mammal-infecting DNA viruses identified in lemurs and rodents in Madagascar mirror the evolutionary history of their hosts.

Paietta EN, Johnston RA, Kraberger S, et al. Mammal-infecting DNA viruses identified in lemurs and rodents in Madagascar mirror the evolutionary history of their hosts. Microbial genomics. 2026;12(5). doi:10.1099/mgen.0.001728

Genetic Drivers of Sensitivity or Resistance to RAS(ON) Multi-Selective Inhibitors in NRAS-Mutated Melanoma.

Foth M, Kim W, O’Toole K, et al. Genetic Drivers of Sensitivity or Resistance to RAS(ON) Multi-Selective Inhibitors in NRAS-Mutated Melanoma. Cancer research. 2026. doi:10.1158/0008-5472.CAN-26-1313

Reimagining HER2 therapy: Bridging oncogene addiction and immune modulation.

Tillman L, Pusztai L, Wander SA, Sundar R, Klempner SJ. Reimagining HER2 therapy: Bridging oncogene addiction and immune modulation. Cancer cell. 2026. doi:10.1016/j.ccell.2026.04.011