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Publications

Somatic hypermutation generates antibody specificities beyond the primary repertoire.

Zuo T, Gautam A, Saghaei S, et al. Somatic hypermutation generates antibody specificities beyond the primary repertoire. Immunity. 2025;58(6):1396-1410.e7. doi:10.1016/j.immuni.2025.04.014

Data Interoperability and Harmonization in Cardiovascular Genomic and Precision Medicine.

Chahal AA, Alahdab F, Asatryan B, et al. Data Interoperability and Harmonization in Cardiovascular Genomic and Precision Medicine. Circulation. Genomic and precision medicine. 2025;18(3):e004624. doi:10.1161/CIRCGEN.124.004624

Early dynamics of clinical and laboratory parameters predict primary refractory disease in patients with metastatic urothelial carcinoma receiving atezolizumab.

Graser CJ, McDonald TO, Catalano PJ, Sonpavde G, Michor F. Early dynamics of clinical and laboratory parameters predict primary refractory disease in patients with metastatic urothelial carcinoma receiving atezolizumab. Journal for immunotherapy of cancer. 2025;13(5). doi:10.1136/jitc-2025-011740

Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses.

Nielsen TT, Bali P, Grove J, et al. Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA psychiatry. 2025;82(8):790-800. doi:10.1001/jamapsychiatry.2025.0828

Pitfalls of bacterial pan-genome analysis approaches: a case study of Mycobacterium tuberculosis and two less clonal bacterial species.

Marin MG, Quinones-Olvera N, Wippel C, et al. Pitfalls of bacterial pan-genome analysis approaches: a case study of Mycobacterium tuberculosis and two less clonal bacterial species. Bioinformatics (Oxford, England). 2025;41(5). doi:10.1093/bioinformatics/btaf219

Patient agency and large language models in worldwide encoding of equity.

Armoundas AA, Loscalzo J. Patient agency and large language models in worldwide encoding of equity. NPJ digital medicine. 2025;8(1):258. doi:10.1038/s41746-025-01598-y

Celeste: A cloud-based genomics infrastructure with variant-calling pipeline suited for population-scale sequencing projects.

Siddiqui N, Lee B, Yi V, et al. Celeste: A cloud-based genomics infrastructure with variant-calling pipeline suited for population-scale sequencing projects. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.04.29.25326690

The multilayered transcriptional architecture of glioblastoma ecosystems.

Nomura M, Spitzer A, Johnson KC, et al. The multilayered transcriptional architecture of glioblastoma ecosystems. Nature genetics. 2025;57(5):1155-1167. doi:10.1038/s41588-025-02167-5

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics.

Spitzer A, Johnson KC, Nomura M, et al. Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics. Nature genetics. 2025;57(5):1168-1178. doi:10.1038/s41588-025-02168-4

Eclipse: a Python package for alignment of two or more nontargeted LC-MS metabolomics datasets.

Hitchcock DS, Krejci JN, Sturgeon CE, et al. Eclipse: a Python package for alignment of two or more nontargeted LC-MS metabolomics datasets. Bioinformatics (Oxford, England). 2025;41(6). doi:10.1093/bioinformatics/btaf290