Rare coding and noncoding variants map 1,342 diseases and biomarkers in 490,549 whole genomes. Yuan Y, Guan Y, Feng Y, et al. Rare coding and noncoding variants map 1,342 diseases and biomarkers in 490,549 whole genomes. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.24.26349148 PMCID PMC13042129 Read more
A population-scale atlas of blood and tissue in lupus nephritis. Sugiarto NW, Gurajala S, Curtis M, et al. A population-scale atlas of blood and tissue in lupus nephritis. bioRxiv : the preprint server for biology. 2026. doi:10.1101/2025.08.11.669754 PMCID PMC13060338 Read more
High-throughput biochemical phenotyping of SHP2 variants reveals the molecular basis of diseases and allosteric drug inhibition. Lee AA, Mokhtari DA, Egan ED, Blacklow SC, Herschlag D, Fordyce PM. High-throughput biochemical phenotyping of SHP2 variants reveals the molecular basis of diseases and allosteric drug inhibition. bioRxiv : the preprint server for biology. 2026. doi:10.64898/2026.03.30.715055 PMCID PMC13060101 Read more
Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin Resistance. Garcia-Urena M, Toh PJY, Martinez RS, et al. Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin Resistance. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.31.26349822 PMCID PMC13060440 Read more
Deep learning-based stratification of Schizophrenia Spectrum Disorder from real-world data reveals distinct profiles of common and rare variant genetic signal. Cobuccio L, Avellà MP, Webel H, et al. Deep learning-based stratification of Schizophrenia Spectrum Disorder from real-world data reveals distinct profiles of common and rare variant genetic signal. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.30.26349393 PMCID PMC13060403 Read more
, a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss. Liedtke D, Rak K, Schrode KM, et al. , a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss. medRxiv : the preprint server for health sciences. 2026. doi:10.64898/2026.03.27.26349271 PMCID PMC13060437 Read more
Lipoprotein(a)-Associated Proteomic Signature Predicts Cardiovascular Disease in Young Adults. Goonewardena SN, Yao S, Jurga T, et al. Lipoprotein(a)-Associated Proteomic Signature Predicts Cardiovascular Disease in Young Adults. The Journal of clinical investigation. 2026. doi:10.1172/JCI204287 Read more
Objectively Measured Daytime Napping Patterns and All-Cause Mortality in Older Adults. Gao C, Cai R, Zheng X, et al. Objectively Measured Daytime Napping Patterns and All-Cause Mortality in Older Adults. JAMA network open. 2026;9(4):e267938. doi:10.1001/jamanetworkopen.2026.7938 Read more
Community-led standards for global wastewater-based infectious disease surveillance. Smith EA, Jeshvaghane MA, Pilz DA, et al. Community-led standards for global wastewater-based infectious disease surveillance. PLOS global public health. 2026;6(4):e0006266. doi:10.1371/journal.pgph.0006266 Read more
Associations of Combined Genetic and Lifestyle Risks With Incident Type 2 Diabetes in the UK Biobank. Zhao C, Hatzikotoulas K, Balasubramanian R, et al. Associations of Combined Genetic and Lifestyle Risks With Incident Type 2 Diabetes in the UK Biobank. Diabetes. 2026;75(5):860-866. doi:10.2337/db25-0672 Read more