Publications

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels.

Tanzo JT, Li VL, Wiggenhorn AL, et al. CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels. The Journal of biological chemistry. 2023:104764. doi:10.1016/j.jbc.2023.104764

SynapseCLR: Uncovering features of synapses in primary visual cortex through contrastive representation learning.

Wilson A, Babadi M. SynapseCLR: Uncovering features of synapses in primary visual cortex through contrastive representation learning. Patterns (New York, N.Y.). 2023;4(4):100693. doi:10.1016/j.patter.2023.100693

Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency.

Das A, Tabori U, Nahum LCS, et al. Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023. doi:10.1158/1078-0432.CCR-23-0411

Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.

Khoshkhoo S, Wang Y, Chahine Y, et al. Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy. JAMA neurology. 2023. doi:10.1001/jamaneurol.2023.0473

The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.

Weinstock JS, Laurie CA, Broome JG, et al. The genetic determinants of recurrent somatic mutations in 43,693 blood genomes. Science advances. 2023;9(17):eabm4945. doi:10.1126/sciadv.abm4945

Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-binding protein LIN28 and Let-7.

Borgelt L, Huang F, Hohnen L, et al. Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-binding protein LIN28 and Let-7. Chembiochem : a European journal of chemical biology. 2023:e202300168. doi:10.1002/cbic.202300168

Geographic variation in the association between Hashimoto's thyroiditis and Papillary thyroid carcinoma, a meta-analysis.

Sweis NWG, Zayed AA, Jaberi MA, et al. Geographic variation in the association between Hashimoto’s thyroiditis and Papillary thyroid carcinoma, a meta-analysis. Endocrine. 2023. doi:10.1007/s12020-023-03378-8

Association of distinct microbial signatures with premalignant colorectal adenomas.

Lee JWJ, Plichta DR, Asher S, et al. Association of distinct microbial signatures with premalignant colorectal adenomas. Cell host & microbe. 2023;31(5):827-838.e3. doi:10.1016/j.chom.2023.04.007

Effect of CD274 (PD-L1) overexpression on survival outcomes in 10 specific cancers: a systematic review and meta-analysis.

Park JH, Luchini C, Nottegar A, et al. Effect of CD274 (PD-L1) overexpression on survival outcomes in 10 specific cancers: a systematic review and meta-analysis. Journal of clinical pathology. 2023. doi:10.1136/jcp-2023-208848

Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease.

Amarasekera SSC, Hock DH, Lake NJ, et al. Multi-omics identifies large mitoribosomal subunit instability caused by pathogenic MRPL39 variants as a cause of pediatric onset mitochondrial disease. Human molecular genetics. 2023. doi:10.1093/hmg/ddad069