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Publications

Discovering small-molecule senolytics with deep neural networks.

Wong F, Omori S, Donghia NM, Zheng EJ, Collins JJ. Discovering small-molecule senolytics with deep neural networks. Nature aging. 2023. doi:10.1038/s43587-023-00415-z

Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes.

Phillips EA, Silverman AD, Joneja A, et al. Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes. Nature biomedical engineering. 2023. doi:10.1038/s41551-023-01028-y

Sound and light levels in intensive care units in a large urban hospital in the United States.

Leone MJ, Dashti HS, Coughlin B, et al. Sound and light levels in intensive care units in a large urban hospital in the United States. Chronobiology international. 2023:1-10. doi:10.1080/07420528.2023.2207647

Matrix prior for data transfer between single cell data types in latent Dirichlet allocation.

Min A, Durham T, Gevirtzman L, Noble WS. Matrix prior for data transfer between single cell data types in latent Dirichlet allocation. PLoS computational biology. 2023;19(5):e1011049. doi:10.1371/journal.pcbi.1011049

A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma.

Alladina J, Smith NP, Kooistra T, et al. A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma. Science immunology. 2023;8(83):eabq6352. doi:10.1126/sciimmunol.abq6352

Evolution of the crustal phosphorus reservoir.

Walton CR, Hao J, Huang F, et al. Evolution of the crustal phosphorus reservoir. Science advances. 2023;9(18):eade6923. doi:10.1126/sciadv.ade6923

Genetic events associated with venetoclax resistance in CLL identified by whole exome sequencing of patient samples.

Khalsa JK, Cha J, Utro F, et al. Genetic events associated with venetoclax resistance in CLL identified by whole exome sequencing of patient samples. Blood. 2023. doi:10.1182/blood.2022016600

Single-cell analysis reveals inflammatory interactions driving macular degeneration.

Kuchroo M, DiStasio M, Song E, et al. Single-cell analysis reveals inflammatory interactions driving macular degeneration. Nature communications. 2023;14(1):2589. doi:10.1038/s41467-023-37025-7

The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.

Huerta-Chagoya A, Schroeder P, Mandla R, et al. The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. Diabetologia. 2023. doi:10.1007/s00125-023-05912-9

Relationship of HPV16 E6 seropositivity with circulating tumor tissue modified HPV16 DNA before head and neck cancer diagnosis.

Rettig EM, Waterboer T, Sim E, et al. Relationship of HPV16 E6 seropositivity with circulating tumor tissue modified HPV16 DNA before head and neck cancer diagnosis. Oral oncology. 2023;141:106417. doi:10.1016/j.oraloncology.2023.106417