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Publications

Personalized circulating tumor DNA dynamics inform survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer.

Ruiz-Torres DA, Merkin RD, Bryan ME, et al. Personalized circulating tumor DNA dynamics inform survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer. NPJ precision oncology. 2025;9(1):298. doi:10.1038/s41698-025-01084-4

Brain Organoids: Tools for Understanding the Uniqueness and Individual Variability of the Human Brain.

Faravelli I, Antón-Bolaños N, Brown JR, Arlotta P. Brain Organoids: Tools for Understanding the Uniqueness and Individual Variability of the Human Brain. Annual review of genomics and human genetics. 2025;26(1):299-320. doi:10.1146/annurev-genom-111522-014009

Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes.

Kong BS, Lee H, L’Yi S, Hong S, Cho YM. Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes. Experimental & molecular medicine. 2025;57(8):1861-1877. doi:10.1038/s12276-025-01521-1

The mitotic STAG3-cohesin complex shapes male germline nucleome.

Nagano M, Hu B, Ogata K, et al. The mitotic STAG3-cohesin complex shapes male germline nucleome. Nature structural & molecular biology. 2025. doi:10.1038/s41594-025-01647-w

Longitudinal Antibody Responses to SARS-CoV-2 Infection in Children: Impact of Age, Vaccines and Symptoms.

Ma P, Chen PD, Jadhav S, et al. Longitudinal Antibody Responses to SARS-CoV-2 Infection in Children: Impact of Age, Vaccines and Symptoms. The Pediatric infectious disease journal. 2025. doi:10.1097/INF.0000000000004949

Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS.

Szewczyk B, Zimyanin V, Japtok J, et al. Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS. Cell reports. 2025;44(9):116113. doi:10.1016/j.celrep.2025.116113

Cell Type Distribution of Intrathecal Antisense Oligonucleotide Activity in Deep Brain Regions of Non-Human Primates.

Frei JA, Gentile JE, Lian Y, et al. Cell Type Distribution of Intrathecal Antisense Oligonucleotide Activity in Deep Brain Regions of Non-Human Primates. Nucleic acid therapeutics. 2025. doi:10.1177/21593337251371594

IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk.

Zhang L, Omarov M, Xu L, deGoma E, Natarajan P, Georgakis MK. IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk. Nature cardiovascular research. 2025;4(9):1172-1186. doi:10.1038/s44161-025-00700-7

Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology.

Lee HG, Rone JM, Li Z, et al. Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology. Nature. 2025;645(8081):E5. doi:10.1038/s41586-025-09546-2

Author Correction: Complex genetic variation in nearly complete human genomes.

Logsdon GA, Ebert P, Audano PA, et al. Author Correction: Complex genetic variation in nearly complete human genomes. Nature. 2025;645(8081):E6. doi:10.1038/s41586-025-09547-1