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Publications

Privacy-preserving genotype imputation in a trusted execution environment.

Dokmai N, Kockan C, Zhu K, Wang X, Sahinalp C, Cho H. Privacy-preserving genotype imputation in a trusted execution environment. Cell Syst. 2021. doi:10.1016/j.cels.2021.08.001

Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery.

Segel M, Lash B, Song J, et al. Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. Science. 2021;373(6557):882-889. doi:10.1126/science.abg6155

Implementation of SARS-CoV2 Screening in K-12 Schools Using In-School Pooled Molecular Testing and Deconvolution by Rapid Antigen Test.

Pollock NR, Berlin D, Smole SC, et al. Implementation of SARS-CoV2 Screening in K-12 Schools Using In-School Pooled Molecular Testing and Deconvolution by Rapid Antigen Test. J Clin Microbiol. 2021;59(9):e0112321. doi:10.1128/JCM.01123-21

Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery.

Qin W, Myers SA, Carey DK, Carr SA, Ting AY. Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery. Nat Commun. 2021;12(1):4980. doi:10.1038/s41467-021-25259-2

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes.

Genshaft AS, Ziegler CGK, Tzouanas CN, et al. Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nat Commun. 2021;12(1):4995. doi:10.1038/s41467-021-25279-y

A unified model of human hemoglobin switching through single-cell genome editing.

Shen Y, Verboon JM, Zhang Y, et al. A unified model of human hemoglobin switching through single-cell genome editing. Nat Commun. 2021;12(1):4991. doi:10.1038/s41467-021-25298-9

Clonally expanded, GPR15-expressing pathogenic effector T2 cells are associated with eosinophilic esophagitis.

Morgan DM, Ruiter B, Smith NP, et al. Clonally expanded, GPR15-expressing pathogenic effector T2 cells are associated with eosinophilic esophagitis. Sci Immunol. 2021;6(62). doi:10.1126/sciimmunol.abi5586

Optimized liquid and gas phase fractionation increases HLA-peptidome coverage for primary cell and tissue samples.

Klaeger S, Apffel A, Clauser KR, et al. Optimized liquid and gas phase fractionation increases HLA-peptidome coverage for primary cell and tissue samples. Mol Cell Proteomics. 2021:100133. doi:10.1016/j.mcpro.2021.100133

Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease.

Lee JWJ, Plichta D, Hogstrom L, et al. Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease. Cell Host Microbe. 2021;29(8):1294-1304.e4. doi:10.1016/j.chom.2021.06.019

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations.

Stražar M, Temba GS, Vlamakis H, et al. Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations. Nat Commun. 2021;12(1):4845. doi:10.1038/s41467-021-25213-2