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Publications

Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging.

Tomov ML, O’Neil A, Abbasi HS, et al. Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging. Commun Biol. 2021;4(1):786. doi:10.1038/s42003-021-02276-x

Acquired Resistance to KRAS Inhibition in Cancer.

Awad MM, Liu S, Rybkin II, et al. Acquired Resistance to KRAS Inhibition in Cancer. N Engl J Med. 2021;384(25):2382-2393. doi:10.1056/NEJMoa2105281

Mass spectrometry-based HLA-II peptidomics combined with multi-omics will aid the development of future immunotherapies.

Taylor HB, Klaeger S, Clauser KR, et al. Mass spectrometry-based HLA-II peptidomics combined with multi-omics will aid the development of future immunotherapies. Mol Cell Proteomics. 2021:100116. doi:10.1016/j.mcpro.2021.100116

STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.

Adane B, Alexe G, Seong BKA, et al. STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma. Cancer Cell. 2021;39(6):827-844.e10. doi:10.1016/j.ccell.2021.05.007

Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts.

Cruz DL, Pipalia N, Mao S, et al. Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts. ACS Pharmacol Transl Sci. 2021;4(3):1136-1148. doi:10.1021/acsptsci.1c00033

B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.

Scheid JF, Barnes CO, Eraslan B, et al. B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV. Cell. 2021;184(12):3205-3221.e24. doi:10.1016/j.cell.2021.04.032

Gene fusions create partner and collateral dependencies essential to cancer cell survival.

Gillani R, Seong BKA, Crowdis J, et al. Gene fusions create partner and collateral dependencies essential to cancer cell survival. Cancer Res. 2021. doi:10.1158/0008-5472.CAN-21-0791

Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.

Wilhelm M, Zolg DP, Graber M, et al. Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics. Nat Commun. 2021;12(1):3346. doi:10.1038/s41467-021-23713-9

Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence.

Wu Z, Zhou J, Zhang X, et al. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nat Genet. 2021;53(6):881-894. doi:10.1038/s41588-021-00859-2

MalDA, Accelerating Malaria Drug Discovery.

Yang T, Ottilie S, Istvan ES, et al. MalDA, Accelerating Malaria Drug Discovery. Trends Parasitol. 2021;37(6):493-507. doi:10.1016/j.pt.2021.01.009